雌雄激素受体与膀胱癌预后的关系  

The Relationship between Estrogen and Androgen Receptors and Prognosis of Bladder Transitional Cell Carcinoma

作　　者：魏强[1] 李世文[2] 李虹[1] 杨宇如[1] 邓显昭 唐孝达[1] 姚先莹[3] 

机构地区：[1]华西医科大学附属第一医院泌尿外科,成都610041 [2]湖北医科大学附属第二医院泌尿外科,武汉430071 [3]华西医科大学附属第一医院病理科,成都610041

出　　处：《医学新知》2000年第2期62-64,共3页New Medicine

摘　　要：采用荧光组织化学法测定了 89例膀胱移行细胞癌雌雄激素受体的表达 ,获长期随访的 77例中有 32例复发 ,复发率为 41.5 6 %。采用乘积限法计算受体表达阳性各组及阴性组肿瘤复发率并进行比较。结果提示膀胱癌复发率随雌激素受体表达增多有下降趋势 ,但无统计学显著差异 ;雄激素受体表达阳性与否亦与肿瘤复发率无关。Estrogen receptor(ER) and Androgen receptor(AR) assays were performed with fluorescent histochemical method in 89 cases of bladder carcinoma.77 cases were followed up for at leazt six years.The tumor recurrence occurred in 32(41.56%). Product limit estimates were used to calculate the recurrence rate.The results showed: there was not statistic difference of recurrence rate between ER positive and negative groups. There wasn’t either statistic difference of recurrence rate between AR positive and negative groups.

关 键 词：膀胱癌 复发 性激素受体 预后 

分 类 号：R737.14[医药卫生—肿瘤]