异戊醛一步合成异戊酸异戊酯  

One-step Synthesis of Isoamyl Isovalerate from Isovaleraldehyde

作　　者：郑来昌 索纪栓[2] 曹镭 

机构地区：[1]兰州炼油化工总厂石化研究院,甘肃兰州730060 [2]中国科学院兰州化学物理研究所,甘肃兰州730000

出　　处：《精细化工》2000年第7期381-383,385,共4页Fine Chemicals

摘　　要：在自制的异戊醇铝催化剂和无水氯化锌助催化剂作用下 ,以异戊醛为原料一步合成出异戊酸异戊酯。对影响反应的因素作了考察 ,以收率为指标时其主次顺序为 :[m(ZnCl2 )∶m(异戊醇铝 ) ]>异戊醇铝用量 >反应温度 >反应时间 ;并且确定出反应的最佳工艺条件为 :w(异戊醇铝 ) =1 0 %,m(ZnCl2 )∶m(异戊醇铝 ) =0 5∶1 0 ,反应温度 2 0℃ ,反应时间 5h ;在此工艺条件下异戊酸异戊酯收率和选择性分别可达 87%和 98%以上。用气相色谱、质谱和红外光谱对合成产物做了定性、定量分析。The simple method of one step synthesis of isoamyl isovalerate from isovaleraldehyde under aluminum isoamyloxide catalyst and ZnCl\-2 co catalyst was studied.The sequence of primary influencing factors of reaction was m(ZnCl\-2)∶ m(aluminum isoamyloxide) >the amount of aluminum isoamyloxide>the reaction temperature>the reaction time. Optimum rection conditions were as follows: amount of aluminum isoamyloxide 10%, mass ratio of ZnCl\-2 to aluminum isoamyloxide 0 5∶1 0, rection temperature 20 ℃,and rection time 5 h.Under these conditions,the yield and selectivity of isoamyl isovalerate was over 87% and 98% respectively.The synthesiszed compound was analyzed by GS,MS and IR.

关 键 词：异戊酸异戊酯 异戊醛 歧化 一步法 合成 

分 类 号：TQ225.241[化学工程—有机化工] TS264.3[轻工技术与工程—发酵工程]