高脂血症性急性胰腺炎的临床分析  

The clinical analysis of hyperlipidemic acute pancreatis

作　　者：肖丽[1] 王玉倩[1] 陈明[1] 赵金满[1] 

机构地区：[1]中国医科大学附属第一医院消化内科,沈阳110001

出　　处：《临床内科杂志》2012年第9期610-611,共2页Journal of Clinical Internal Medicine

摘　　要：目的探讨高脂血症性急性胰腺炎（HAP）的临床特点，以提高人们对此病的认识。方法回顾性分析我院2005年1月-2010年12月收治的148例急性胰腺炎（AP）患者的临床资料，通过对HAP与非HAP的比较，探讨HAP的临床特点。结果在148例AP患者中HAP31例（20．95％），与其他原因的AP比较，HAP的血脂异常主要表现为三酰甘油升高（P〈0．05），HAP发病与胆固醇升高无相关性；HAP患者的糖尿病和脂肪肝发病率与其他原因所致的胰腺炎比较，差异有统计学意义（P〈0．05）；HAP患者的血淀粉酶正常或略升高。结论高三酰甘油血症和胰腺炎的发病密切相关，是AP的第3大病因。与其他原因所致胰腺炎比较，HAP组的血淀粉酶正常或轻度升高，其临床表现不典型，并发症多，易复发。Objective To investigate the clinical characteritics of hyperlipidemic acute pancreatitis（HAP）. Methods 148 cases of acute pancreatitis（AP） patients were retrospectively analyzed from Jan. 2005 to Dec. 2010 in the First Affiliated Hospital of Chinese Medical Univercity. By comparing with the pancreatitis patients caused by other reasons ,the clinical characteritics of hyperlipidemic acute panereatitis were investigated. Results Of the 148 AP cases,31 patients had HAP（20.95% ）. Compared with the pancreatitis patients caused by other reasons, serum tfiglyceride （TG） instead of serum total cholesterol （TC） in HAP patients increased significantly（ P 〈0.05 ） ,the difference in the incidence of diabetes and fatty liver was significant between these 2 types pancreatitis （P 〈 0.05 ）. The hemodiastase in HAP is norreal or moderately elevated. Conclusion Following the cholangitis and alcoholic, hypertriglyceridemia is the third reason of AP and was closely related to pancreatitis. In comparison with the other causes of pancreatitis, the patients with HAP have normal or moderately elevated hemodiastase, atypical clinical manifestation, more complications and recurrence.

关 键 词：急性胰腺炎 高脂血症 

分 类 号：R576[医药卫生—消化系统]