急性脑梗死中医证型与血小板活化关系研究  

Study on the Relationship TCM Syndromes of Acute Cerebral Infarction and Platelet Activation

作　　者：符布清[1] 姜鹏君[2] 彭丽晨[1] 于顾然[1] 季明德[1] 王佳[1] 

机构地区：[1]江苏省中医院检验科,江苏南京210029 [2]江苏省中医院神经内科,江苏南京210029

出　　处：《辽宁中医杂志》2012年第10期1907-1909,I0001,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：江苏省中医药管理局课题(HLZ09028)

摘　　要：目的:探讨急性脑梗死不同中医证型血小板活化的演变规律。方法:对急性脑梗死患者进行中医辨证分型,测定101例急性脑梗死患者和30例健康对照组体内LPA、AP和CD62P水平。结果:急性脑梗死患者阳亢腑实组、痰瘀阻络组、气虚血瘀组CD62P、LPA、AP水平明显高于健康对照组(P<0.01);而阳亢腑实组、痰瘀阻络组、气虚血瘀组各组CD62P、LPA、AP水平之间比较无显著性差异(P>0.05)。结论:急性脑梗死患者各中医证型均表现血小板活化增高,但各证型之间血小板活化水平无明显差异。Objective：to explore the different syndrome type of traditional Chinese medicine in acute cerebral infarction platelet activating evolution. Methods： on acute cerebral infarction patients with TCM syndrome differentiation, were measured in 101 patients with acute cerebral infarction and 30cases of healthy controls in LPA,AP and CD62P levels. Results：in acute cerebral infarction patients with hyperactivity of Yang Fu real group, phlegm and blood stasis group, Qi deficiency and blood stasis group CD62P,LAP,AP levels were significantly higher than those in the control group（ P 〈 0. 01 ） ;Yang Kang Fu and real group, phlegm and blood stasis group, Qi deficiency and blood stasis syndrome group CD62P, LAP, AP levels between compared no sig- nificant difference （ P 〉 0.05 ）. Conclusion ： the TCM syndromes in patients with acute cerebral infarction were shown to platelet ac- tivation is increased, but the syndrome type of platelet activation levels were not significantly different between.

关 键 词：急性脑梗死 血浆溶血磷脂酸 溶血磷脂酸相似磷脂 CD62P 中医证型 

分 类 号：R743.33[医药卫生—神经病学与精神病学]