论“毒瘀交阻”是胃癌前病变高危证型的核心病机  

Analysis on the Core Role of Combination of Toxin and Blood Stasis on Pathogenesis of High-risk Syndrome of Precancerous Lesion of Gastric Cancer

作　　者：王捷虹[1] 宇文亚[2] 惠建萍[1] 梁海云[3] 

机构地区：[1]陕西中医学院附属医院脾胃病科,陕西咸阳712083 [2]中国中医科学院,北京100700 [3]陕西中医学院,消化专业研究生陕西咸阳712046

出　　处：《辽宁中医杂志》2012年第10期1958-1959,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(30873266)

摘　　要：文章提出了"毒瘀交阻"是胃癌前病变(PLGC)发生癌变的核心病机,气阴两虚是产生"毒瘀交阻"的体虚条件的学说。并论述了湿热蕴胃与幽门螺杆菌感染相关性,湿热毒邪滞气凝络是产生毒瘀交阻的病理结局,以及通过临床研究验证了解毒化瘀兼益气养阴法能有效阻止PLGC癌变。This paper presents the combination of toxin and blood stasis is the core pathogenesis that makes precancerous le- sion of gastric cancer（PLGC） cancerous, and asthenia of both Qi and Yin is cause of toxin and blood stasis. And it discusses the relationship between damp-heat retention in the stomach and Helicobacter pylori infection, damp-heat pathogen blocking Qi and meridian is the pathological outcome that causes combination of toxin and blood stasis, and verifies that methods of eliminating tox- in, resolving blood stasis, supplementing Qi and nourishing Yin can effectively prevent PLGC cancerous by clinical studies.

关 键 词：胃癌前病变 毒瘀交阻 核心病机 临床研究 

分 类 号：R735.2[医药卫生—肿瘤]