儿童全身^(18)F-FDG PET/CT辐射剂量评估  

Evaluation of Radiation Dose in Pediatric Whole-Body Dual-Modality ^(18)F-FDG PET/CT Examinations

作　　者：吴震宇[1] 王辉[1] 

机构地区：[1]上海交通大学医学院附属新华医院核医学科,200092

出　　处：《放射免疫学杂志》2012年第5期494-497,共4页Journal of Radioimmanology

摘　　要：目的:研究和评估受检儿童在全身PET/CT显像中所受到的辐射剂量,并讨论其可能受到的辐射损伤。方法:选取60例接受全身PET/CT显像儿童患者(<18岁),在自动曝光技术下通过公式估算出CT和PET的全身有效剂量值,将估算结果与国外类似报道结果比较。结果:单次PET/CT显像,受检儿童所受CT有效剂量为(2.8～10.8)mSv,平均(5.9±1.8)mSv;PET有效剂量为(4.5～12.4)mSv,平均(7.2±2.0)mSv;PET/CT总有效剂量为(8.55～20.2)mSv,平均(13.1±2.9)mSv;CT有效剂量占总有效剂量比例为45.2%;年龄越大,CT所导致的辐射剂量也越大;自动曝光技术下儿童全身PET/CT辐射剂量明显低于固定能量PET/CT扫描。结论:配备有AEC技术的PET/CT单次检查所致辐射剂量对受检儿童来说是安全的。Objective To evaluate the radiation dose of children patient in whole-body dual-modality 18F-FDG PET/CT examinations and discuss the possibility of radiation damage.Methods PET/CT studies on 60 children and teen-age youths patient（〈18y） were retrospectively reviewed.The effective dose of PET/CT was the summation of CT and PET dosimetry estimated by the conversion formula with automatic exposure control（AEC） technique.Result The mean dose of an individual CT study was 5.9±1.8mSv（range： 2.8 to 10.8 mSv）,of PET study was 7.2±2.0mSv（range： 4.5to 12.4 mSv） and of PET/CT study was 13.1±2.9mSv（range： 8.5 to 20.2 mSv）.The proportion of dose due to CT scan is 45.2%.The effective dose due to CT scan ascend with age.Divice equipped with AEC technique can provide lower dose than fixed energe divice significantly.Conclusion Individual whole-body dual-modality 18F-FDG PET/CT examination equipped with AEC technique provides safety for children.

关 键 词：儿童 正电子发射型计算机断层显像 有效剂量 辐射 自动曝光技术 

分 类 号：R739.41[医药卫生—肿瘤]