不可切除转移性结直肠癌的治疗策略  

Treatment strategies of unresectable metastatic colorectal cancer

作　　者：蔡浩权[1] 林英城[1] 

机构地区：[1]汕头大学医学院附属肿瘤医院内科,515031

出　　处：《国际肿瘤学杂志》2012年第10期775-778,共4页Journal of International Oncology

摘　　要：化疗或联合分子靶向治疗仍是不能手术切除转移性结直肠癌的主要手段。对于一线治疗后获得疾病控制的患者，间歇治疗和维持治疗等新策略的疗效可能不劣于持续给药至疾病进展或不能接受毒性为止的传统策略，而且可以减少药物相关不良反应和提高生活质量。Chemotherapy with or without molecule-targeting agents is the primary choice for patients with unreseetable metastatic colorectal cancer. New treatment strategies like intermittent therapy and mainte- nance therapy may not inferior to treatment until progression or unacceptable toxicity in maintaining the benefit for patients who responded or had stable disease after the first-line therapy, and also can reduce the drug related side effects and improve the quality of life.

关 键 词：结直肠肿瘤 肿瘤转移 药物疗法 

分 类 号：R735.34[医药卫生—肿瘤]