动脉瘤性蛛网膜下腔出血术后低钠血症相关危险因素分析及临床特点  

Aneurysmal subarachnoid hemorrhage postoperative hyponatremia risk factors and clinical features

作　　者：昝向阳[1] 

机构地区：[1]新疆医科大学附属中医医院神经外科,新疆乌鲁木齐830000

出　　处：《现代预防医学》2012年第20期5471-5472,5475,共3页Modern Preventive Medicine

摘　　要：目的探讨动脉瘤性蛛网膜下腔出血术后低钠血症发生的相关危险因素,观察动脉瘤性蛛网膜下腔出血术后低钠血症的临床特点。方法回顾性分析2004年3月～2011年4月126例在某院收治的动脉瘤性蛛网膜下腔出血患者的临床资料,分析术后低钠血症的相关危险因素及临床特点。结果 126例患者中有35例术后并发低钠血症,占27.78%。将性别、年龄、术前Hunt-Hess分级、动脉瘤部位、手术时机等危险因素引入二项分类Logistic回归分析模型之中,性别、手术时机等与低钠血症发生无关,差异无统计学意义(P﹥0.05),年龄、动脉瘤部位、术前Hunt-Hess分级等与低钠血症发生有关,差异有统计学意义(P﹤0.05)。结论年龄、动脉瘤部位、术前Hunt-Hess分级等与低钠血症发生有关,50～60岁之间,前交通动脉瘤,术前Hunt-Hess分级级别越高,其术后并发低钠血症的可能性越大。OBJECTIVE To investigate the risk factors associated with aneurysmal subarachnoid hemorrhage, postoperative hyponatremia occurred, and the clinical features observed after aneurysmal subaraehnoid hemorrhage hyponatremia. METHODS Retrospective analysis was used for the clinical data of 126 eases in our hospital with aneurysmal subaraehnoid hemorrhage in Mareh 2004 to April 2011. We analyzed the risk factors associated with postoperative hyponatremla and clinical characteristics. RESULTS Among 126 patients, 35 eases were postoperative hyponatremia, accounting for 27.78%. Risk factors included gen der, age, preoperative Hunt-Hess grade, aneurysm site and the timing of surgery. Logistic regression analysis model showed gender and timing of surgery had no association with hyponatremia （P〉 0.05） Age and aneurysm site had association with pre operative Hunt-Hess grade hyponatremia （P〈 0.05）. CONCLUSION Age, aneurysm site, preoperative Hunt-Hess grade had association with hyponatremia. Ages of 50-60, the anterior communicating artery aneurysm, Hunt-Hess grade level the higher the preoperative and postoperative are the risk factors for hyponatremia.

关 键 词：动脉瘤 蛛网膜下腔出血 动脉瘤夹闭术 低钠血症 HUNT-HESS分级 

分 类 号：R743.35[医药卫生—神经病学与精神病学]