尼莫地平和依达拉奉治疗高血压性脑出血的疗效对比研究  

Comparative Study of Nimodipine and Edaravone's Efficacy for Treatment of Hypertensive Intracerebral Hemorrhage

作　　者：窦鹏[1] 丁军峰[2] 王文海[1] 

机构地区：[1]淄博广电医院神经内科,山东淄博255000 [2]淄博广电医院放射科,山东淄博255000

出　　处：《中外医疗》2012年第26期8-9,共2页China & Foreign Medical Treatment

摘　　要：目的比较尼莫地平和依达拉奉治疗高血压性脑出血的临床疗效及安全性。方法选取该院收治的高血压性脑出血患者60例为研究对象,随机分为尼莫地平组和依达拉奉组各30例,比较两组患者治疗后临床疗效和不良反应发生情况。结果治疗后尼莫地平组总有效率高于依达拉奉组,差异有统计学意义(P<0.05);两组治疗后血肿体积及水肿带体积均较治疗前减小(P<0.05),且两组治疗后比较,尼莫地平组各参数均较依达拉奉组降低(P<0.05)。结论两种药物治疗高血压性脑出血均有疗效,且无严重不良反应发生,但尼莫地平应用更安全、有效。Objective To compare the efficacy and safety of Nimodipine and Edaravone for treatment of hypertensive intracerebral hemorrhage patients.Method Select 60 patients with hypertensive intracerebral hemorrhage admitted to our hospital,randomly divided into 30 cases of the nimodipine group and the edaravone group,the patients were compared clinical efficacy and adverse reaction.Results The total effective rate of nimodipine was significantly higher than edaravone group,the difference was statistically significant（P0.05）;After treatment,hematoma volume and edema volume compared with treatment were decrease（P0.05）,and the two groups after treatment,the parameters of the nimodipine group compared with the edaravone group decreased（P0.05）.Conclusions The two drugs for treatment of hypertensive cerebral hemorrhage have effect,and no serious adverse reactions occurred,but the application of nimodipine are more safe and effective.

关 键 词：尼莫地平 依达拉奉 高血压性脑出血 疗效 

分 类 号：R743.34[医药卫生—神经病学与精神病学]