铒(Er)-L-组氨酸-邻菲啰啉三元配合物的合成与性质  

Synthesis and properties of rare earth (Er)-L-histidine-1,10-phenanthroline ternary complex

作　　者：王卫东[1] 李登科[1] 李晓慧[1] 胡远亮[2] 陈灵[1] 陆江林[1] 

机构地区：[1]湖北师范学院化学与环境工程学院,湖北黄石435002 [2]湖北师范学院生命科学学院,湖北黄石435002

出　　处：《化学研究与应用》2012年第10期1549-1554,共6页Chemical Research and Application

基　　金：湖北省教育厅重点科研项目(D20082202)资助

摘　　要：在乙醇介质中,合成了铒(Er)-组氨酸(L-His)-邻菲啰啉(Phen.H2O)三元稀土配合物,利用摩尔电导率、络合滴定分析、元素分析、红外光谱(IR)和热重-差热(TG-DTA)等分析测试,推测配合物的化学组成为:[Er(L-His)3Phen]Cl3.3H2O。初步研究了配合物的电化学性质和生物活性;其中稀土配合物对革兰氏阴性菌大肠杆菌、革兰氏阳性枯草芽孢杆菌都有较好的抑制作用,特别是对革兰氏阴性菌大肠杆菌抑制效果更好。并通过循环伏安测定了配合物在铂盘工作电极上的电化学行为,在HAc-NaAc缓冲溶液(pH≈6.0)中ErCl3.6H2O和配合物{[Er(L-His)3Phen]Cl3.3H2O}在-0.3 V～-1.0 V(vs.SCE)电位范围内均表现出电化学活性,配合物的电化学活化中心是Er3+,该配合物为准可逆体系,且配合物的还原峰电流与浓度和扫描速率呈现递增关系。In ethanol medium, one solid ternary complex of Rare earth（Er） and histidine acid（L-His） and 1,10-phenanthroline （ Phen·H2 O） was synthesized. It was inferred to be [ Er （L-His） 3 Phen ] C13 - 3 H20 using molar conductance, complexometric titra- tion analysis,elemental analysis,infrared spectra（IR） and TG-DTA analysis test and so on. This article studied on electrochemical property and biological activitY preliminary of complex. Rare earth complex of Gram-negative bacteria escherichia coli, and Gram- positive bacillus subtilis had a better inhibitory role, especially for Gram-negative bacteria escherichia coli. Its electrochemical be- havior at a platinum working electrode was tested by cyclic voltammetry. The complex [ Er（L-His） 3 Phen ] Cl3·3 H2O and ErCl3·6H2O had shown the electrochemical activitY at-0. 3 V - -1.0 V（vs. SCE）in the HAc-NaAc buffer solution（pHi6.0）. The Er3＋ was electrochemical active center in rare earth complex. The results showed that the complex was a quasi-reversible system and it showed the increasing relationship between the coordination compound＇s reduction peak and concentration and scan rate.

关 键 词：三元稀土配合物 红外光谱 循环伏安 电化学活性 抑菌效应 

分 类 号：O614.3[理学—无机化学]