激光辅助孵出对冻融胚胎着床潜能的影响  

Effects of laser Assisted hatching on the ability of frozen-thawed embryo implantation

作　　者：杜湧瑞[1] 张云山[1] 姚汝强[1] 罗海宁[1] 鲁振宇[1] 王毅娜[1] 

机构地区：[1]天津市中心妇产科医院生殖医学中心,天津300100

出　　处：《陕西医学杂志》2012年第10期1316-1318,共3页Shaanxi Medical Journal

摘　　要：目的:探讨激光辅助孵出(LAH)对前次冻融胚胎移植失败患者临床妊娠率及胚胎种植率的影响。方法:对前次IVF-ET失败并排除子宫内膜、胚胎质量等因素的116例患者,根据是否采用激光辅助孵化分为LAH组(56例)和对照组(60例),对LAH组患者的胚胎采用部分透明带薄化后进行移植。比较两组患者临床妊娠率和胚胎种植率。结果:LAH组的临床妊娠率为53.3%,与对照组的36.7%比较差异有显著性(P<0.05),胚胎种植率为29.3%,显著高于对照组的17.9%(P<0.05)。结论:LAH可提高前次FET失败患者的临床妊娠率和胚胎种植率。Objective：To investigate the effects of laser assisted hatching （LAH） on clinical pregnancy rate and embryo implantation rate in patients with previous frozen -thawed embryo transfer （FET） failure cycle. Methods：A total of 116 patients with previous FET failure cycle, without endometria and embryo quality factors, randomly assigned to either control group （56） or LAH group （60） according to whether subjected to LAH. Clinical pregnancy rate and embryo implantation rate were compared in two groups. Results：The pregnancy and implantation rates were significantly higher than that in 56 thinning group compared to control group respectively （53.3% vs. 36. 7%, P〈0.05;29.3% vs. 17.9%,P〈0.05）. Conclusion： The laser assisted hatching may increase the pregnancy and implantation rates in patients of previous frozen-thawed failure cycle.

关 键 词：生殖技术 辅助 胚胎植入 激光 

分 类 号：R717[医药卫生—妇产科学]