二氧化硅负载硫酸氢钠催化合成对羟基苯甲酸正丁酯  

Synthesis of n-butyl p-hydroxybenzoate with sodium bisulfate supported by silica

作　　者：孔祥文[1] 李召静[1] 于龙[1] 

机构地区：[1]沈阳化工大学应用化学学院,沈阳110142

出　　处：《食品科技》2012年第10期227-230,共4页Food Science and Technology

基　　金：辽宁省教育科学"十一五"规划立项课题高校精品课程建设的理论与实践研究项目(JG09DB112);辽宁省教育厅高等学校科学研究项目(202092009)

摘　　要：以对羟基苯甲酸和正丁醇为原料,二氧化硅负载硫酸氢钠为催化剂,合成了对羟基苯甲酸正丁酯。考察了影响合成反应的诸多因素。结果表明,合成对羟基苯甲酸正丁酯的优化工艺条件为:醇酸摩尔比为3:1、催化剂用量为反应物总质量的5%、回流反应3h,在此条件下,酯化率可达96.2%。通过红外光谱验证了目标产物。催化剂具有一定的重复使用活性。Preparation of n-butyl p-hydroxybenzoate by the esterification of p-hydroxy benzoic acid and n-butanol using sodium bisulfate as a catalyst supported by silica was reported. The influences of some factors on the synthesis process were studied. The optimal reaction conditions were chosen that the molar ratio of n-butanol and p-hydroxy benzoic acid was 3：1, the mass ratio of catalyst to reactants was 5%, reaction time by refluing was 3 hours. The yield of the product reached 96.2%. The structure of n-butyl p-hydroxybenzoate was characterized by IR spectrum. The catalyst could be recycled and used for many times.

关 键 词：对羟基苯甲酸正丁酯 酯化反应 催化 二氧化硅 硫酸氢钠 合成 

分 类 号：TS202.3[轻工技术与工程—食品科学]