子宫内膜癌盆腔淋巴结转移相关因素分析  

Relative Factors of Pelvic Nodal Metastasis in Endometrial Carcinoma

作　　者：于美玲[1] 张晓霞[1] 钟艳平[2] 张松灵[1] 

机构地区：[1]吉林大学第一医院妇产科,长春130021 [2]吉林大学第一医院病理科,长春130021

出　　处：《肿瘤防治研究》2012年第10期1233-1235,共3页Cancer Research on Prevention and Treatment

基　　金：国家自然科学基金青年基金资助项目(30901589);中国博士后科学基金资助项目(20100480171)

摘　　要：目的探讨子宫内膜癌患者盆腔淋巴转移的相关因素及其意义。方法子宫内膜癌247例分为伴有淋巴结转移组及不伴有淋巴结转移组,对两组病例的病理类型、病理分级、肌层浸润、宫颈间质浸润及脉管浸润的关系进行统计学分析。结果伴有淋巴结转移中高分化者占28.57%,低分化占33.33%;不伴有淋巴结转移组中高分化占49.56%,低分化占12.83%,两组差异有统计学意义(P<0.05)。伴有淋巴结转移组中,无肌层浸润0例,肌层浸润深度<1/2占33.33%,肌层浸润深度≥1/2占66.67%,脉管浸润占47.62%,宫颈浸润占47.62%;不伴有淋巴结转移组中,无肌层浸润占11.5%,肌层浸润深度<1/2占66.81%,肌层浸润深度≥1/2占21.68%,脉管浸润占7.08%,宫颈浸润病例占7.96%,两组差异有统计学意义(P<0.05)。结论脉管浸润、宫颈间质浸润、肌层浸润深度≥1/2及低分化与子宫内膜癌盆腔淋巴结转移有相关性,是子宫内膜癌盆腔淋巴结转移的高危因素。Objective To evaluate the relative factors of the pelvic nodal metastasis in endometrial carcino ma. Methods Total 247 patients were collected from January 2009 to July 2010. According to with or without lymph node metastasis,we divided 247 patients into two groups. The relationship between lymph node metastasis and pathologic types,grades, depth of myometrial invasion and cervical invasion was analyzed. Results In groups with lymph node metastasis, 28.57 % was G1,33.33 % was G3,66.67% had invasive more than 1/2 myometrium,47.62 % was invaded vessel and cervical of the total respectively. In groups without lymph node metastasis,49.56% was G1,12.83% was G3,21. 68% invaded more than 1/2 myometrium,Which invaded vessel and cervical was 7.08% and 7.96%, respectively. Conclusion Invasive more than 1/2 myometrium,G3, vessel and cervical invasion are high risk factors for pelvic nodal metastasis in endometrial cancer.

关 键 词：子宫内膜癌 盆腔淋巴结转移 高危因素 

分 类 号：R737.33[医药卫生—肿瘤]