黄斑程序蓝/黄视野检查评估糖尿病性黄斑囊样水肿视功能的研究  

Blue-on-yellow visual field perimetry in evaluating visual function of diabetic cystoid macular edema

作　　者：刘嫣[1] 丁慰祖[1] 姚慧萍[1] 许宇东[1] 钱钧[1] 叶芳[1] 张菊荣[1] 

机构地区：[1]上海市第八人民医院眼科,200235

出　　处：《眼科新进展》2012年第10期960-962,共3页Recent Advances in Ophthalmology

基　　金：上海市六院联合体医疗集团科学研究基金~~

摘　　要：目的探讨黄斑程序蓝/黄视野检查在糖尿病性黄斑囊样水肿(cystoid macular edema,CME)诊断、预后判断及视功能评估中的作用。方法收集糖尿病视网膜病变(diabetic retinopathy,DR)发生CME患者28例(28眼)(CME组),无CME患者24例(24眼)(NCME组),采用瑞士Octopus101型全自动视野计黄斑程序分别进行白/白视野(white-on-white perimetry,W/WP)和蓝/黄视野(blue-on-yellow perimetry,B/YP)检查,记录视野平均光敏感度(mean sensitivity,MS)值、平均缺损(mean defect,MD)值等指标。结果在W/WP检查中,NCME组MS值(26.23±2.71)dB显著大于CME组MS值(23.91±3.37)dB,差异有显著统计学意义(P<0.01);NCME组MD值(1.99±1.27)dB显著小于CME组MD值(4.33±1.92)dB,差异也有显著统计学意义(P<0.01)。在B/YP检查中,NCME组MS值(20.08±2.16)dB显著大于CME组MS值(15.13±2.24)dB,差异有显著统计学意义(P<0.01);NCME组MD值(6.63±2.30)dB显著小于CME组MD值(11.59±3.46)dB,差异有显著统计学意义(P<0.01)。W/WP检查MS(r=-0.357,P=0.009)、MD(r=-0.584,P<0.01),与DR患者有无CME显著相关;B/YP检查MS(r=-0.753,P<0.01)、MD(r=-0.645,P<0.01),也与DR患者有无CME显著相关。结论视野检查尤其是黄斑程序B/YP是糖尿病性CME临床诊断、视功能评估的方法之一,可以作为DR常规检查项目,有利于CME的早期发现及疗效观察。Objective To discuss the value of blue-on-yellow perimetry in diagnosis,prognosis and evaluating visual function for diabetic cystoid macular edema （CME）.Methods Patients with diabetic retinopathy （DR） were selected in this study.Twenty-eight patients （28 eyes） with CME （CME group） and 24 patients （24 eyes） without CME （NCME group） underwent white-on-white perimetry （W/WP） and blue-on-yellow perimetry （B/YP） with Octopus 101 automatic perimetry. The data of mean sensitivity （MS） and mean defect （MD） were compared and analyzed.Results In W/WP,MS in NCME group （26.23±2.71） dB was obviously higher than that in CME group （23.91±3.37） dB,there was significant difference（P0.01）;MD in NCME group （1.99±1.27） dB was obviously smaller than that in CME group （4.33±1.92） dB,there was significant difference（P0.01）.In B/YP,MS in NCME group （20.08±2.16） dB was obviously higher than that in CME group （15.13±2.24） dB,there was significant difference（P0.01）;MD in NCME group （6.63±2.30） dB was obviously smaller than that in CME group （11.59±3.46） dB,there was significant difference（P0.01）.MS （r=-0.357,P=0.009） and MD（r=-0.584,P0.01） in W/WP were correlated with the diagnosis of CME.MS（r=-0.753,P0.01） and MD（r=-0.645,P0.01） in B/YP were correlated with the diagnosis of CME.Conclusion Perimetry is one of the effective tools for detecting CME caused by DR,especially the blue-on-yellow perimetry,which can be set as the routine examination for DR to early diagnose the CME.

关 键 词：糖尿病视网膜病变 黄斑囊样水肿 蓝/黄视野检查 

分 类 号：R774.5[医药卫生—眼科]