湿性年龄相关性黄斑变性OCT特点与视力的相关研究  

Relationship of vision and characteristic of optical coherence tomography in wet age-related macular degeneration

作　　者：王慧娟[1] 杨佳[1] 唐由之[1] 秦虹[1] 郝进[1] 

机构地区：[1]中国中医科学院眼科医院,北京100040

出　　处：《中国实用眼科杂志》2012年第10期1183-1185,共3页Chinese Journal of Practical Ophthalmology

基　　金：“十一五”国家科技支撑计划项目（2006BAl04A20）

摘　　要：目的研究湿性年龄相关性黄斑变性OCT图像特征与患者视力的相关性。方法纳入湿性年龄相关性黄斑变性患者106例106只眼，记录患者最佳矫正视力（EDTRS视力），并对患者眼底进行光学相干断层扫描分析，统计黄斑区视网膜厚度、黄斑区总容积、测量脉络膜新生血管膜厚度，脉络膜新生血管与黄斑中心凹距离。结果患者视力与脉络膜新生血管病变的最大线性距离、黄斑区总容积、CNV厚度、CNV距中心凹距离呈明显相关关系（P〈0．05）。结论湿性年龄相关性黄斑变性患者中心视力与脉络膜新生血管病变的位置、大小、视网膜水肿程度明密切相关。Objective To observe the relationship of vision and characteristic of optical coher- ence tomography （OCT） in wet age-related macular degeneration. Methods A total of 106 eyes with 106 patients were recorded with best corrected visual acuity （EDTRS）, examined with OCT. Sta- tistic central foveal thickness, macular total volume, thickness of choroidal neovascularization, dis- tance between choroidal neovascularization and central fovea of macular. Results There were signifi- cant negative correlation between vision and the greatest linear diameter of lesion, macular total vol- ume, thickness of choroidal neovascularization, distance between choroidal neovascularization and cen- tral fovea of macular （P 〈0.05）. Conclusions The vision of wet age-related macular degeneration is closely related with the location, size of choroidal neovascnlarization and edema degree of retina.

关 键 词：黄斑变性 光学相干 视力 脉络膜新生血管 

分 类 号：R774.5[医药卫生—眼科]