添加益生菌的低脂高蛋白肠内营养制剂在炎症性肠病中的疗效观察  

Clinical observation on application of probiotics combined with low fat high protein enteral nutrition for patients of inflammatory bowel disease

作　　者：孙丽娟[1] 薛森海[1] 闫凤[1] 信丽艳[1] 赵长海[1] 

机构地区：[1]第四军医大学西京医院营养科,陕西西安710032

出　　处：《肠外与肠内营养》2012年第5期260-262,共3页Parenteral & Enteral Nutrition

摘　　要：目的:观察添加益生菌的低脂高蛋白肠内营养(EN)制剂对炎症性肠病(IBD)病人的治疗效果。方法:总结104例IBD病人的临床资料,按照使用EN不同,分为试验组(n=48)和对照组(n=56)。试验组病人使用添加益生菌的低脂高蛋白EN制剂,对照组使用常规EN制剂。所有病人在入院时和营养支持第14天分别测定营养指标和免疫指标等。结果:试验组病人前清蛋白、血小板计数、淋巴细胞明显高于对照组(P﹤0.05),同时达到目标营养液供给量的时间和腹泻发生率亦明显低于对照组(P﹤0.05)。结论:添加益生菌的低脂高蛋白EN比普通EN更能改善IBD病人的营养状况和改善肠道功能。Objective： To observe the efficacy of probiotics combined with low fat high protein enteral nutrition in patients with inflammatory bowel disease.Methods： From March 2007 to February 2012,104 patients with IBD receiving enteral nutritional support were included in this retrospective analysis.The patients were divided into test group and control group according to the kinds of enteral nutrition,the former was supported by probiotics low fat high protein nutritious solution,and the later was treated with common enteral nutritious solution.A series of parameters including nutritional indicators,immune parameters were tested before and 14 days after nutrition therapy.The efficacy of two groups was analyzed and compared.Results： The pre-albumin,platelet and lymphocytes count in test group were significantly higher than control group（P﹤0.05）,and time of reaching target nutrition amount and the incidence rate of diarrhea in test group were lower than in control group.Conclusion： For patients of inflammatory bowel disease,their nutrition status and intestinal function can be modulated more effectively with probiotics combined with low fat high protein enteral nutrition.

关 键 词：炎症性肠病 溃疡性结肠炎 克罗恩病 营养治疗 

分 类 号：R574.62[医药卫生—消化系统] R459.3[医药卫生—内科学]