常见颅内肿瘤与ABO血型的相关性研究  

Correlation study of common intracranial tumors and ABO blood groups

作　　者：朱德龙[1] 彭玉平[1] 漆松涛[1] 樊俊[1] 刘华[1] 

机构地区：[1]南方医科大学南方医院神经外科,广州510515

出　　处：《中国微侵袭神经外科杂志》2012年第10期437-439,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的研究3种常见颅内肿瘤(胶质瘤、脑膜瘤、垂体腺瘤)病人的ABO血型分布。方法对1 923例病理诊断为胶质瘤(n=863)、脑膜瘤(n=732)、垂体腺瘤(n=328)的病人行ABO血型分析,并与相关文献报道的正常人ABO血型分布进行比较。结果 3种颅内肿瘤病人的ABO血型分布与正常人的差异具有统计学意义(P<0.05),A型和O型血个体易患颅内肿瘤(OR值分别为1.12、1.28)。胶质瘤病人B型血、O型血构成比较正常人存在明显差异(均P<0.05),O型血个体更易患胶质瘤(OR值为1.25);脑膜瘤病人A型血、B型血、O型血构成比较正常人存在明显差异(均P<0.05),A型和O型血个体更易患脑膜瘤(OR值分别为1.19、1.34);垂体腺瘤病人O型血构成比明显高于正常人(P<0.05),O型血个体更易患垂体腺瘤(OR值为1.22)。结论颅内肿瘤的发生与ABO血型存在一定的关系。Objective To study the distribution of ABO blood groups of 3 kinds of common intmcranial tumors including glioma, meningioma and pituitary tumor. Methods The distribution of ABO blood groups of 1 923 patients with intracranial tumors verified by pathological diagnosis was analyzed, including glioma in 863 patients, meningioma in 732 and pituitary tumor in 328. The distributions of ABO blood groups were compared between patients with intracranial tumors and health adults reported by literature. Results There was a significant difference in the distribution of ABO blood groups between patients with intmcranial tumors and health people （P 〈 0.05）. Type A and Type O individuals were prone to suffer intracranial tumors （OR = 1.12, 1.28 respectively）. There were significant differences in composition ratios of type B and type O between patients with glioma and health adults （both P 〈 0.05）. Type O individuals were prone to suffer glioma （OR = 1.25）. There were significant differences in composition ratios of type A, type B and type O patients of meningioma and health adults （all P 〈 0.05）. Type A and type O individuals were prone to suffer meningioma （OR = 1.19, 1.34 respectively）. The composition ratio of type O patients with pituitary tumor was significantly higher than that of health adults （P 〈 0.05）. Type O individuals were prone to suffer pituitary tumor （OR = 1.22）. Conclusions There are certain relationships between the intmcranial tumors and ABO blood groups.

关 键 词：颅内肿瘤 ABO血型 相关性 

分 类 号：R739.41[医药卫生—肿瘤]