红比霉素等不同药物组成的二种化疗方案治疗成人急非淋白血病疗效比较  

Combination chemotherapy for acute nonlymphocytic leukemia in adult: A comparison of two schedules

作　　者：楼方定[1] 周绮[1] 孟凡义[1] 刘海川[1] 汪月增[1] 

机构地区：[1]中国人民解放军军医进修学院血液科

出　　处：《军医进修学院学报》1990年第4期289-291,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：本文报告用DATV和DA方案治疗成人急性非淋巴细胞(急非淋)白血病21例的疗效。DATV组11例有10例取得完全缓解(CR),CR率为90.9％;DA组10例有7例取得CR,CR率为70％,两组总的CR率80.5％。初步结果表明,DATV与DA方案相比,其CR率无明显差别(P>0.05)。From December 1987 to November 1989, twenty-one adult patients with acute nonlymphocytic leukemia were treated with DATV (daunorubicin, Ara-C, 6-TG and VCR) and DA (daunorubicin and Ara-C) program. Complete remission (CR) was obtained in 10/11 patients (90.9%) with the former and in 7/10 patients (70%) with the latter. The total remission rate in patients with two prbtocols was 80.5%. We concluded initially that the CR rate with program DATV and DA is very similar (p>0.05). Long continued CR was seen in patients treated with autologous bone marrow trarrow transplantation or early intensification chemotherapy after CR. More patients are needed to evaluate the efficacy of DATV and DA protocol on the CR rate and remission duration more reasonably.

关 键 词：白血病 药物疗法 阿糖胞苷 柔红霉素 

分 类 号：R733.7[医药卫生—肿瘤]