针刺理疗对体外受精周期子宫内膜及卵泡膜血流影响的研究  

Effects of combined acupuncture and intracavitary short-wave physiotherapy on endometrial receptivity in IVF-ET

作　　者：孙振高[1] 连方[1] 张建伟[2] 吴海萃[2] 张竹梅[1] 郭颖[1] 薛明明 张宁[2] 孟茜[1] 赵帅[2] 

机构地区：[1]山东中医药大学附属医院生殖中心,济南250011 [2]山东中医药大学临床学院,济南250014

出　　处：《生殖医学杂志》2012年第5期447-450,共4页Journal of Reproductive Medicine

基　　金：国家自然基金委基金项目(30901920);山东省自然基金资助项目(Q2008C17);山东省中医药科技发展计划项目(2009 038)

摘　　要：目的观察腔内短波理疗联合针刺对体外受精-胚胎移植(IVF-ET)患者子宫内膜及卵泡膜血流的影响,并对治疗结局进行评价。方法将97例IVF患者随机分为腔内短波理疗联合针刺组(治疗组,51例)和单纯西药组(对照组,46例),观察两组注射人绒毛膜促性腺激素(hCG)日子宫内膜厚度、分型及子宫内膜血流阻力指数(RI),以及两组取卵数、优卵率、受精率、优胚率以及临床妊娠率。结果 hCG日子宫内膜厚度,两组比较无显著性差异(P>0.05);A型内膜在治疗组所占比例为74.5%(38/51),在对照组组为45.7%(21/46),两组间有显著差异(P<0.01);治疗组hCG日卵泡膜RI显著低于对照组(P<0.01);两组患者取卵个数、受精率无显著差异(P>0.05),治疗组优卵率、优质胚胎率及临床妊娠率均显著提高(P<0.05)。结论针刺理疗能显著改善IVF-ET患者的子宫内膜及卵泡膜血流,从而改善治疗结局。Objective： To investigate the effects of combined acupuncture and intraeavitary short-wave therapy on endometrial receptivity during in vitro fertilization and embryo transplantation （IVF-ET） and evaluate the treatment outcome. Methods： Ninety seven patients IVF-ET were randomized into two groups. Fifty one patients were received acupuncture and intracavitary short-wave physiotherapy in group A, and 46 patients were only administered western medicine in group B. The clinical data including endometrial thickness and type, endometrial blood flow resistance index （RI） on the day of injecting hCG, number of retrieved oocytes, high quality oocytes rate, fertilization rate, high quality embryos rate and clinical pregnancy rate were compared between the two groups respectively. Results： The difference in endometrial thickness on the day of injecting hCG between the two groups was not statistically significant （P 〉 0. 05）. The proportion of type A endometrium was 74. 5% （38/ 51 cases） in the group A and 45.7% （21/46 cases） in the group B, and the difference between the two groups was statistically significant （P〈0.01）. RI was significantly lower in group B than that in group A（P〈0.01）. No difference was found in the number of retrieved oocytes and the fertilization rate between the two groups （P〉0.05）. The high quality of oocyte rate, embryo rates and clinical pregnancy rate in the group A were all higher than those in the group B （P〈0.05）. Conclusions： Combined acupuncture and intracavitary short-wave therapy could improve endometrial receptivity of patients with IVF-ET, and hence led to superior outcome from treatment.

关 键 词：腔内短波理疗 针刺 体外受精一胚胎移植 临床妊娠率 

分 类 号：R[医药卫生]