功能性消化不良患者钡餐胃动力检查与胃泌素观察  

The value of gastric barium meal dynamic radiography for functional dyspepsia

作　　者：赵青[1] 金玉莲[1] 洪洋[1] 方继良[1] 韦小燕[1] 刘志顺[1] 

机构地区：[1]中国中医科学院广安门医院放射科,北京100053

出　　处：《中国中西医结合影像学杂志》2012年第5期404-407,共4页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：国家重点基础研究发展计划(973计划)(编号:2011CB505202)

摘　　要：目的:研究功能性消化不良(FD)患者钡餐后胃动力与血清胃泌素及临床症状评分变化的相关关系。方法:根据罗马Ⅲ标准纳入17例FD患者(FD组),进行临床FD评分,检测空腹血清胃泌素,行空腹胃钡餐动态摄影检查,与10例正常人(正常人组)对比。胃钡餐动态摄影主要测量指标包括:胃潴留液高度、胃中间横带宽度、蠕动波频率、蠕动波最大宽度、蠕动波最大深度、蠕动波通过时间;胃泌素检查采用钡餐当天清晨空腹血清学检查。对FD患者临床评分与FD胃动力检测各项指标及胃泌素之间进行相关性分析。使用SPSS 13.0软件,采用配对t检验或符号秩检验;相关性分析采用统计软件Sas 8.2简单线性相关及Spearman秩相关指数分析。结果:FD患者与正常人临床症状评分差异有统计学意义(P=0.0000)。FD患者与正常人血清胃泌素水平差异有统计学意义(P=0.006 3)。FD患者与正常人胃动力检测指标胃潴留液高度、胃中间横带宽度、蠕动波频率、蠕动波通过时间差异有统计学意义(P=0.0000;P=0.0000;P=0.000 2;P=0.000 6)。上腹疼痛与胃蠕动波频率呈负相关,胃泌素与钡餐胃动力指标无明显相关性。结论:胃钡餐动态摄影可直观观察胃动力变化,胃泌素体现了胃动力相关激素水平,可作为评价FD及其疗效的客观指标。Objectives：To evaluate the gastric barium meal dynamic radiography in the diagnosis of functional dyspepsia（FD）in patients with gastric motility abnormality.Methods：Seventeen FD patients（group A）were recruited by the Rome III criteria controlled with ten healthy volunteers（group B）.FD Questionaire was scored by all subjects.They all received the examination of the gastric barium meal dynamic radiography（one minute video）and the blood-draw of serum gastrin before breakfast.The imaging indexes included the height of gastric retention liquid,the width of midgastric transverse band（MTR）,the frequency、width and depth of stomach wave.The correlation analysis was performed between the imaging indexes and the FD scores and the serum gastrin using SPSS 13.0.Results：It showed significant differences between FD patients and healthy subjects with the imaging indexes including the height of gastric retention liquid,the width of midgastric transverse band（MTR）,the frequency of stomach wave（P=0.0000;P=0.0000;P=0.0002）.The frequency of stomach wave was correlated with the clinical symptom of upper abdominal pain（P=0.0445,r=-0.71889）.The serum gastrin of FD patients was decreased significantly than the healthy.Conclusion：The gastric barium meal dynamic radiography can directly observe the gastric motility.It is a simple method for detailed evaluation of gastric motility without the use of intragastric catheters that influence gastric physiology.It can be a tool for evaluation of gastric function in both research and clinical settings.

关 键 词：消化不良 胃肠活动 放射摄影术 硫酸钡 胃泌素类 

分 类 号：R57[医药卫生—消化系统]