Cajal间质细胞与消化系统疾病  

The relationship between interstitial cell of Cajal and digestive system disease

作　　者：邵畅[1] 金晓明[1] 

机构地区：[1]哈尔滨医科大学病理学教研室,哈尔滨150081

出　　处：《实用肿瘤学杂志》2012年第5期464-468,共5页Practical Oncology Journal

基　　金：基金项目：黑龙江省教育厅重点项目（12521z017）

摘　　要：自1893年Cajal间质细胞（ICC）被发现以来，关于其生理功能和起搏机制的研究持续至今，ICC的变化与疾病发生机制的关系也随之成为研究的焦点。近年来的临床实验与动物模型研究表明，ICC的数量减少和网络结构的破坏与消化系统疾病的发生相关，为消化系统疾病病因的研究和疾病的治疗方案提供了理论基础。本文将探究ICC在消化系统疾病中的病理变化及其与疾病的关系。Since the discovery of the interstitial cell of Cajal in 1983, there have been continuous studies on its physiological function and the pacing mechanism, where the relationship between the variation of ICC and the emergence of disease have drawn most attention. Recent studies from the clinical experiment and animal test have shown that digestive system diseases are closely related to the decline in the number of ICC and the damage of network. Therefore, they have provided theoretical foundation for the cause and treatment of digestive diseases. This paper dedicates to the pathological variation of the ICC in digestive diseases as well as their relationship.

关 键 词：CAJAL间质细胞 消化系统疾病 肠神经系统 

分 类 号：R363.2[医药卫生—病理学]