膳食质量与冠心病关系的病例对照研究  

ASSESSMENT OF DIET QUALITY RELATED TO CORONARY HEART DISEASE:A CASE-CONTROL STUDY

作　　者：汪敏 张园 李昕睿 吕小飞 陈裕明[2] 凌文华 

机构地区：[1]广东省营养膳食与健康重点实验室 [2]医学统计与流行病学系,广州510080 [2]中山大学公共卫生学院,广州510080

出　　处：《营养学报》2012年第5期436-440,444,共6页Acta Nutrimenta Sinica

基　　金：国家自然科学基金(No.81130052);广州市科技局(No.2010J-E301)

摘　　要：目的应用膳食质量指数(DQI)评价膳食因素与冠心病发病风险的关系。方法采用病例对照研究(冠心病病例342例,健康对照571例)设计,利用食物频率问卷获得膳食数据,依据国际通用的膳食评价方法 DQI计算并比较两组研究对象的膳食质量指数评分;通过非条件Logistic回归模型分析DQI评分与冠心病的关系。结果病例组DQI评分高于对照组,在非条件Logistic回归模型中,校正了非膳食因素的影响,DQI最高三分位数组(膳食质量较差)与最低三分位数组(膳食质量较好)比较,OR值为1.690(95%CI:1.139-2.507)。进一步对首次诊断为冠心病的病例组与对照组比较,OR值为1.803(95%CI:1.083-3.001)。结论冠心病人的膳食质量较健康对照差,膳食质量越差,冠心病人的发病风险越高,人们需要重视整体膳食质量,降低冠心病发病的危险性。Objective To investigate the relationship between dietary factors and coronary heart disease（CHD） using the diet quality index（DQI）.Method 342 CHD patients and 571 healthy controls were entrolled in the case-control study.Diet information was obtained by using food frequency questionnaire.DQI scores were calculated and compared between groups.Unconditional logistic regression model was used to asses the relationship between DOI scores and CHD risk.Results The patients’ DQI was higher than that of the controls.In the unconditional logistic regression model,the OR was 1.690（95% CI：1.139-2.507） in the comparison between the highest and lowest tertile of DQI scores after the effect of non-diet factors were adjusted.Further comparison was carried out between the newly diagnosed CHD patients to healthy controls and the OR was 1.803（95% CI：1.083-3.001）.Conclusion The diet quality of CHD patients was worse than that of healthy controls.The worse the diet quality was,the more the CHD risk.In order to prevent CHD,more attention should be paid to the whole diet quality.

关 键 词：膳食因素 膳食质量指数 冠心病 病例对照研究 

分 类 号：R151.4[医药卫生—营养与食品卫生学] R459.3[医药卫生—公共卫生与预防医学]