急性脑梗死经rt—PA溶栓治疗的临床疗效观察  

Acute Cerebral Infarction rt-PA Thrombolytic Therapy Clinical Curative Effect Obsewation

作　　者：王立岐[1] 周秀玉[1] 朱春雨[1] 张继红[1] 解洪荣[1] 钟志强[1] 李雪松[1] 宫旭海[1] 

机构地区：[1]大庆油田总医院,黑龙江大庆163001

出　　处：《医学信息》2012年第9期145-145,共1页Journal of Medical Information

摘　　要：目的观察重组组织型纤溶酶原激活物（rt—PA）溶栓治疗急性脑梗死的疗效及安全性。方法急性脑梗死患者20例，分为溶栓组和对照组各10例。溶栓组采用rt—PA0．9mg／kg；对照组采用低分子右旋糖酐500ml加丹参川芎嗪20ml静滴。用欧洲脑卒中临床肾经缺损评分标准（ESS）Bathel指数进行疗效评定。结果r-tPA组疗效明显高于对照组（P〈0．01）。结论rt-PA治疗急性脑梗死的临床疗效是安全、有效的。Objective To investigate the safety , and efficacy in acute ischemic stroke patients treated with intravenous recombinant tissueplasminogen activator（rt-PA）. Methods 20 patients with acute cerebral infarction were randomly divided into r-tPA group（ 10例） and control group（ 10例）. rt- PA was administered in a dose of 0. 9mg/kg body weight. Whereas the control group received only routine treatment. The neurologic function deficits of patients in both groups were evaluated by ESS and Barthel index. Results rt-PA treatment was significantly higher than control group. Conclusion rt-PA can be performed safely and efficaciously in patients with acute cerebral infarction.

关 键 词：rt—PA 急性脑梗死 溶栓 临床疗效 

分 类 号：R743.33[医药卫生—神经病学与精神病学]