穿支动脉疾病型缺血性卒中的临床特点  

Clinical characteristics of penetrating artery disease type ischemic stroke

作　　者：张奕文[1] 牛建平[1] 彭瑞强[1] 宋叶华[1] 徐娜[1] 蔡继福[1] 

机构地区：[1]厦门市第二医院神经内科,361021

出　　处：《齐齐哈尔医学院学报》2012年第19期2597-2599,共3页Journal of Qiqihar Medical University

摘　　要：目的探讨穿支动脉疾病(penetrating artery disease,PAD)型缺血性卒中的临床特点,为临床提供借鉴。方法对78例PAD型缺血性卒中患者与192例非PAD型缺血性卒中患者的人口学分布、部分卒中危险因素、入院时NIHSS评分、溶栓率、进展性脑梗死的发生率进行分析,并进一步对两组缺血性卒中的进展特点,包括进展停止时NIHSS增加值及不合理降压、感染、血糖水平对两组卒中进展的影响进行对比分析,同时还对两组接受溶栓的病例溶栓后继续进展的发生率进行对比分析。结果两组人口学分布、部分卒中危险因素、溶栓率差异无统计学意义。但是,PAD型缺血性卒中入院时NIHSS评分较低,进展性脑梗死发生率较低,进展停止时NIHSS评分增加较少,不合理降压在PAD组的进展性脑梗死病例中发生率较高以及PAD组接受溶栓病例继续进展的发生率较低,与非PAD型缺血性卒中比较差异有统计学意义。结论与非PAD型缺血性卒中相比较,PAD型缺血性卒中在临床上具有病情相对较轻、较少发生进展、进展程度较轻、不合理降压在该型卒中进展中所起的作用更突出以及溶栓可以更有效地减少该型卒中发生进展的特点。Objective To discuss the clinical characteristics of penetrating artery disease（PAD）type ischemic stroke,and provide reference for clinical. Methods Analyzed the demography distribution,some stroke risk factors,NIHSS grade when hospitalized,thrombolysis rates,and progressive cerebral infarction rates according to 78 patients of PAD type ischemic stroke and 192 patients of non PAD type ischemic stroke.Further,analyzed the two group ischemic stroke features and the influence of two group ischemic stroke,including NIHSS value increasing when progress stopped,unreasonable depressurization,infection,content of blood sugar.In the mean time,compared the progress occurrence rate with two group patients who accept thrombolysis. Results The differences of two group demography distribution,some stroke risk factors,thrombolysis rates don＇t have statistical significance.However,when PAD type ischemic stroke patients got in to hospital,the NIHSS grade was lower,the progressive cerebral infarction rate was lower as well,and the NIHSS value increasing when progress was less,the unreasonable depressurization rates was higher progress cerebral infarction cases in the PAD group,and the progressing occurrence rate was lower in the PAD group who accepted thrombolysis,above differences to the non PAD ischemic stroke had statistical significance. Conclusions Compared with the non PAD ischemic stroke,PAD ischemic stroke has such features in clinical as relatively less illness,progressing less,progress degree lighter,the effect of unreasonable depressurization is more important during progressing in this type,and thrombolysis can decrease the stroke,and make progressing more effectively.

关 键 词：穿支动脉疾病 缺血性卒中 进展性脑梗死 临床特点 

分 类 号：R743.3[医药卫生—神经病学与精神病学]