0.1%西吡氯铵含漱液对牙外伤纤维夹板固定术后菌斑形成的抑制作用  

The effect of mouth rinse containing 0.1% cetylpyridinium chloride in the inhibition of dental plague formation in fiber splinting teeth

作　　者：吴辰[1] 龚怡[1] 杨圣辉[1] 黄薇[1] 

机构地区：[1]首都医科大学附属北京口腔医院急诊科,北京100050

出　　处：《中国微生态学杂志》2012年第10期896-897,900,共3页Chinese Journal of Microecology

摘　　要：目的观察0.1%西吡氯铵含漱液对牙外伤纤维夹板固定术后菌斑形成的抑制作用。方法牙外伤患者40例随机分为2组,应用双盲法分别给予患者0.1%西吡氯铵含漱液漱口(试验组)或0.12%氯己定含漱液漱口(对照组)。每天5次,分别在晨起、睡前、三顿饭后各漱口1次,每次含15 mL,持续漱口60 s,漱口后1 h内禁饮食,7 d为一疗程。就诊当天(1 d)、4 d和8 d,按照Quigley-Hein指数(Turesky改良)测定菌斑指数。结果中期检查试验组和对照组菌斑指数组间比较差异无统计学意义(P>0.05);终点检查试验组和对照组菌斑指数组间比较差异无统计学意义(P>0.05)。结论 0.1%西吡氯铵含漱液可抑制牙外伤纤维夹板固定术后菌斑的形成,有利于牙周损伤的愈合。Objective To observe the effects of mouth rinse containing 0.1% cetylpyridinium chloride in the inhibition of dental plague formation in patients with fiber splinting teeth.Methods 40 cases of injured teeth were enrolled and divided into two groups.Random and double bland method was applied to administer 0.1% cetylpyridinium chloride（tested group） or 0.12% chlorhexidine（control group） to the patients.The mouth rinses were used by the patients for 7 days and 5 times each day（after getting up and each meal,and before going to bed）,each time 15 mL mouth rinse was used for 1 minute.Plague Index（PI,Quigley–Hein Index modified by Turesky） was measured before treatment,on day 4 and 8 respectively.ResultsThe distribution of age,sex and smoking in the tested 20 cases was not significantly different from that of the 20 controls（P〈0.05）.On day 4,there was no statistic difference in the decrease of PI between the two groups（P〈0.05）.On day 8,there was no statistic difference in the decrease of PI between the two groups（P〈0.05）.Conclusion 0.1% cetylpyridinium chloride is effective in the inhibition of dental plague formation in patients with injured teeth.

关 键 词：西吡氯铵含漱液 牙外伤 牙菌斑 

分 类 号：R781.41[医药卫生—口腔医学]