代谢综合征对脑梗死患者颈动脉粥样硬化的影响  

Influence of metabolic syndrome on carotid atherosclerosis in patients with cerebral infarction

作　　者：冯海松[1,2] 黎红华[1] 周佩[3] 杨梅[1] 杨柳[1] 

机构地区：[1]广州军区武汉总医院神经内科,武汉430070 [2]湖北中医药大学 [3]广州军区武汉总医院超声影像科,武汉430070

出　　处：《临床神经病学杂志》2012年第5期378-380,共3页Journal of Clinical Neurology

摘　　要：目的研究代谢综合征(MS)对脑梗死患者颈动脉粥样硬化的影响。方法对30例脑梗死合并MS、37例脑梗死合并高血压和21例单纯脑梗死患者进行颈动脉彩色多普勒超声检查。比较3组患者颈动脉斑块形成状况及其性质。结果脑梗死合并MS组颈动脉粥样硬化斑块的检出率、斑块总数和不稳定斑块数均明显高于脑梗死合并高血压组和单纯脑梗死组(P<0.05～0.01),稳定性斑块数明显高于单纯脑梗死组(P<0.05);颈动脉内-中膜厚度(IMT)、斑块面积亦明显大于脑梗死合并高血压组和单纯脑梗死组(P<0.05～0.01)。脑梗死合并高血压组与单纯脑梗死组以上颈动脉粥样硬化斑块各项指标比较,差异均无统计学意义。结论 MS对脑梗死患者颈动脉粥样硬化的发生和病变程度有显著的影响,并且其影响甚至大于高血压。Objective To investigate the influence of metabolic syndrome （MS） on carotid atherosclerosis in patients with cerebral infarction. Methods The 30 cerebral infraction （ CI ） patients with MS, 37 CI patients with hypertension（HT） and 21 simple CI patients were examined by carotid ultrasound sonography. The conditions of formation and properties of the carotid plaque in these 3 groups were compared. Results The detection rate, total number of carotid plague and unstable plagues in the CI with MS group were significantly higher than those in the CI with HT and simple CI groups（P 〈0. 05 -0.01 ） , and the number of stable plaques was more than that in the simple CI group（ P 〈 0. 05 ） ; the IMT value and the plaques area in MS group were significantly larger than those in CI with HT and simple CI groups （P 〈 0. 05 -0. 01 ）. There ＂was no significant differences in all the indicators above mentioned between the CI with HT group and simple CI group. Conclusion The MS has a significant influence on the formation and pathological degree of carotid atherosclerosis in CI patients, and this effect is even more important than HT.

关 键 词：脑梗死 代谢综合征 颈动脉粥样硬化 

分 类 号：R743.3[医药卫生—神经病学与精神病学]