鼻咽清毒颗粒和鼻可乐冲洗液合用对鼻咽癌患者放疗后的疗效观察  

Clinical study of bi yan qing du ke li and Nasal Care in treatment of patients with nasopharyngeal carcinoma after radiotherapy

作　　者：石华 

机构地区：[1]咸宁市第一人民医院耳鼻咽喉科,湖北咸宁437000

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第21期970-972,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:观察鼻咽清毒颗粒和鼻可乐冲洗液合用对鼻咽癌患者放疗后EB病毒壳抗原抗体VCA/IgA滴度水平和鼻咽部症状的影响。方法:将60例鼻咽癌放疗后患者按就诊顺序分成实验组(鼻咽清毒颗粒和鼻可乐冲洗液合用,30例)和对照组(仅用鼻咽清毒颗粒,30例)。结果:治疗后,实验组显效9例、有效10例、无效11例,总有效率为63.33%,VCA/IgA几何平均滴度为20.5;对照组显效3例、有效8例、无效19例,总有效率为36.66%,VCA/IgA几何平均滴度为55.6。2组总有效率、治疗后VCA/IgA几何平均滴度比较均差异有统计学意义(均P<0.05)。2组患者在治疗过程中均无严重并发症和不良反应发生。结论:鼻咽清毒颗粒和鼻可乐冲洗液合用对鼻咽癌患者放疗后EB病毒VCA/IgA滴度水平有明显的抑制作用,对患者鼻咽部症状有较好的改善作用,可能会有助于降低鼻咽癌的发病率。To investigate the effect of bi yan qing duke li combined with Nasal Care on the titers of EB virus VCA/IgA and nasopharyngeal symptoms in patients with nasopharyngeal carcinoma（NPC） after radiotherapy. Method：Sixty NPC patients underwent-radiotherapy were randomly divided into study group（bi yan qing duke li combined with Nasal Care, n = 30） and control group （hi yan qing du ke li group, n = 30）. Result： After treatment, the geometric mean titer of VCA/IgA was 20.5 in study group and 55.6 in control group, respectively （P〈0.05）. Meanwhile, the nasopharyngeal symptoms after treatment in study group was improved significantly better than that of control group（P〈0.05）. Conclusion：The application of bi yan qing du ke li combined with Nasal Care can significantly decrease the titers of VCA/IgA in NPC patients after-radiotherapy and improve the nasopharyngeal symptoms, which might be helpful to decrease the recurrence rate of NPC.

关 键 词：鼻咽肿瘤 EB病毒VCA/IgA 中药 鼻腔冲洗 

分 类 号：R739.63[医药卫生—肿瘤]