22例口服抗血栓药相关脑出血患者的临床分析  

Clinical analysis of 22 cases of oral antithrombotic therapy related intracerebral hemorrhage

作　　者：夏海龙[1] 孙彦龙[1] 杨刚[1] 

机构地区：[1]重庆医科大学附属第一医院神经外科,400016

出　　处：《重庆医学》2012年第30期3152-3154,共3页Chongqing medicine

摘　　要：目的探讨口服抗血栓药相关脑出血(OAT-ICH)患者的临床特点。方法回顾性分析该院2009年6月至2011年6月收治的22例OAT-ICH患者的临床资料。结果患者预后和死亡率与发病年龄、格拉斯哥昏迷(GCS)评分、出血量、国际标准化比值(INR)、血肿是否扩大关系密切。结论 OAT-ICH具有出血量大,血肿扩大的持续时间长、发生率高、预后更差,凝血功能异常,GCS评分低等特点;防止血肿进一步扩大对改善预后、降低死亡率非常重要;手术治疗是口服OAT-ICH最主要方式,但手术风险大,围术期管理特别关键。Objective To explore the clinical characteristics of oral antithrombotic therapy related intracerebral hemorrhage（OAT-ICH）.Methods The clinic data of 22 cases of OAT-ICH was retrospectively reviewed.Results The prognosis and mortality is related to the age,Glasgow Coma Scale（GCS）score,volume of the hematoma,International Normalized Ratio（INR） and hematoma expansion.Conclusion OAT-ICH has clinical characteristics of large hemotoma volume,common and long time frame for hematoma expansion,worse prognosis if hematoma expansion happens,coagulation defects,low GCS score and so on;To improve the prognosis and lower the mortality,we should focus on preventing the hematoma expansion.Surgical therapy is the main treatment to OAT-ICH even if it has a high risk,more attention should be paid to the perioperative management.

关 键 词：纤维蛋白溶解药 脑出血 临床特征 手术治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]