Immunogenicity of Rcombinant Type 1 Pilus Oil-emulsified Vaccine of Avian Escherichia coli in Chickens  

作　　者：GAN Li-ming JIANG Jia-jin ZHANG Miao ZHANG Zhi-cheng CHEN Zhong-ming DAI Ding-zhen 

机构地区：[1]Jinling Institute of Technology,Nanjing 211196,China

出　　处：《Animal Husbandry and Feed Science》2012年第1期36-37,48,共3页动物与饲料科学（英文版）

基　　金：funded by the Natural Science Foundation of Jiangsu Province ( BK2008059)

摘　　要：[ Objective] To prepare recombinant type 1 pilus vaccine of avian Escherichia coil and to detect its immunogenicity in chickens. [Meth- od] The type 1 pilus was respectively isolated from the recombinant bacteria CZYR10 strain and wild avian Eschedchia co/i YR（ O18 ） strain and used to prepare oil-emulsified vaccine. The immunogenicity of the developed vaccine was detected in chickens using the challenge test. [ Result] The recombinant type 1 pilus protein had immunoprotective efficacy. The recombinant type 1 pilus protein had weaker protective efficacy than the isolated type 1 pilus protein, but the difference was not significant. [ Conclusion] The study provides a reference for immunization and control of chicken colibacillosis.[ Objective] To prepare recombinant type 1 pilus vaccine of avian Escherichia coil and to detect its immunogenicity in chickens. [Meth- od] The type 1 pilus was respectively isolated from the recombinant bacteria CZYR10 strain and wild avian Eschedchia co/i YR（ O18 ） strain and used to prepare oil-emulsified vaccine. The immunogenicity of the developed vaccine was detected in chickens using the challenge test. [ Result] The recombinant type 1 pilus protein had immunoprotective efficacy. The recombinant type 1 pilus protein had weaker protective efficacy than the isolated type 1 pilus protein, but the difference was not significant. [ Conclusion] The study provides a reference for immunization and control of chicken colibacillosis.

关 键 词：Avian Escherichia coil Recombinant type 1 pilus IMMUNOGENICITY 

分 类 号：S858.315.1[农业科学—临床兽医学] S852.612[农业科学—兽医学]