IMMUNOGENICITY

作品数：267被引量：618H指数：12
导出分析报告
相关领域：医药卫生更多>>
相关作者：任爱国马俊荣徐应军冯福民刘崇柏更多>>
相关机构：南京农业大学华北煤炭医学院中国预防医学科学院吉林省兽医科学研究所更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Structural and temporal dynamics analysis on immune response in low-dose radiation:History,research hotspots and emerging trends
《World Journal of Radiology》2025年第4期32-46,共15页Shu-Yuan Wang Jia-Xing Wu Xian An Zhen Yuan Yi-Fan Ren Xiu-Feng Yu Xiao-Dong Tian Wei Wei 
BACKGROUND Radiotherapy(RT)is a cornerstone of cancer treatment.Compared with conven-tional high-dose radiation,low-dose radiation(LDR)causes less damage to normal tissues while potentially modulating immune responses...
关键词：Low-dose radiotherapy Immune response Immunotherapy Bibliometric analysis Radiation-induced immunogenicity Synergistic therapies 
Exploring the role of cationic lipids in modulating immunogenicity and vaccine efficacy of mRNA-LNP
《Particuology》2025年第2期1-11,共11页Yan Zhou Xiangfei Shan Renji Gu Yufei Xia Xiaonan Huang 
This work was supported by National Key Research and Development Program of China(grant No.2021YFC2302400);Major Program of the National Natural Science Foundation of China(grant Nos.T2394503 and T2394501);CAS Project for Young Scientists in Basic Research(grant No.YSBR-010);Key Project of the National Natural Science Foundation of China(grant No.32030062);IPE Project for Frontier Basic Research(grant No.QYJC2023-04)。
The mRNA vaccines have become a transformative platform in medicine,with their success during the COVID-19 pandemic accelerating research in viral prevention and cancer therapy.Lipid nanoparticles(LNPs)enhance the sta...
关键词：Lipid nanoparticle mRNA vaccine IMMUNOGENICITY Cationic lipids Immune response 
Deletion of Salmonella pathogenicity islands SPI-1, 2 and 3 induces substantial morphological and metabolic alternation and protective immune potential
《Journal of Integrative Agriculture》2025年第1期272-289,共18页Gaosong Liu Xuelian Lü Qiufeng Tian Wanjiang Zhang Fei Yi Yueling Zhang Shenye Yu 
supported by the National KeyR&DProgramof China(2022YFF0710500);the National Natural Science Foundation of China(32172853 and 32373013);the Central Public-interest Scientific Institution Basal Research Fund,China(1610302022001).
The Salmonella pathogenicity islands(SPIs) play crucial roles in the progression of Salmonella infection. In this study, we constructed an improved λ Red homologous recombination system to prepare single and triple d...
关键词：Salmonella pathogenicity islands(SPls) morphology carbon source metabolism PATHOGENICITY IMMUNOGENICITY live attenuated vaccine 
Leveraging computer-aided design and artificial intelligence to develop a next-generation multi-epitope tuberculosis vaccine candidate
《Infectious Medicine》2024年第4期53-73,共21页Li Zhuang Awais Ali Ling Yang Zhaoyang Ye Linsheng Li Ruizi Ni Yajing An Syed Luqman Ali Wenping Gong 
sponsored by the Beijing Nova Program(20240484526).
Background:Tuberculosis(TB)remains a global public health challenge.The existing Bacillus Calmette–Guérin vaccine has limited efficacy in preventing adult pulmonary TB,necessitating the development of new vaccines w...
关键词：TUBERCULOSIS Multi-epitope vaccine Computer-aided design Artificial intelligence IMMUNOGENICITY 
Comparison of antigen-specific B cell responses reveals disparity in immunogenicity and memory B cell formation across COVID-19 vaccine platforms
《hLife》2024年第12期626-640,共15页Chang Guo Xin Chai Maidaiti Baerlike Yingping Liu Yao Wang Fei Shao Qingrui Huang Weiguo Zhang Shan Cen Yijie Dong Yunlong Cao Jinghua Yan Xuyu Zhou Zhaolin Hua Baidong Hou 
approved by the Animal Care and Use Committee of the Institute of Biophysics,Chinese Academy of Sciences(SYXK2023171,SYXK2019012).
Various vaccine technologies have been employed in the coronavirus disease 2019(COVID-19)vaccines,including whole inactivated virus(WIV),recombinant protein,mRNA,and nanoparticle vaccines.To elucidate the cellular mec...
关键词：the coronavirus disease 2019(COVID-19)inactivated vaccine mRNA vaccine nanoparticle vaccine IMMUNOGENICITY memory B cells germinal center response 
Immunogenicity Evaluation of a SARS-CoV-2 BA.2 Subunit Vaccine Formulated with CpG 1826 plus alum Dual Adjuvant
《Biomedical and Environmental Sciences》2024年第12期1409-1420,共12页Yuhan Yan Qiudong Su Yao Yi Liping Shen Shengli Bi 
funded by the National Key R&D Program of China(2023YFC2605302).
Objective The present study aimed to evaluate the immunogenicity of BA.2 variant receptor binding domain(RBD)recombinant protein formulated with CpG 1826 plus alum dual adjuvant.Methods The BA.2 variant RBD(residues 3...
关键词：SARS-CoV-2 RBD Subunit vaccine ADJUVANT IMMUNOGENICITY 
Immunogenicity of Short-Course,High-Dose Hepatitis B Vaccination in Patients with Chronic Kidney Disease-Shanxi Province,China,2019-2020
《China CDC weekly》2024年第50期1331-1336,I0002-I0005,共10页Linying Gao Xufeng Cui Xinyuan Mo Zhaoyue Men Xiuyang Xu Tian Yao Jianmin Wang Hongting Liu Hongping Guo Guowei Chai Liming Liu Fuzhen Wang Xiaofeng Liang Suping Wang Yongliang Feng 
Supported by the National Science and Technology Major Project of the Ministry of Science and Technology of the People’s Republic of China under Grant[2018ZX10721202];the Key Research and Development Program of Lvliang under Grant[2020SHFZ52];the Key Research and Development Program of Science and Technology of Linfen under Grant[2136].
What is already known about this topic?As one of the populations at high risk of hepatitis B virus(HBV)infection,patients with chronic kidney disease(CKD)require rapid and effective development of hepatitis B surface ...
关键词：ROUTINE KIDNEY SHANXI 
Current progress of virus-mediated gene therapy-where we are and what we need
《感染控制(英文)》2024年第3期8-20,共13页Wei Miao 
Viral vectors are instrumental in gene therapy and vaccination,addressing a spectrum of diseases from genetic disorders to cancer.Despite their promise,their clinical utility is hampered by the propensity to provoke h...
关键词：viral vectors IMMUNOGENICITY gene therapy innate and adaptive immune systems immune evasion strategies 
Investigation of the epidemiology,pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023被引量：1
《Animal Diseases》2024年第3期156-172,共17页Qinghua Shang Wenhui Gao Xiangting Zhang Jianqing Zhao Ying Wu Haoqi Li Ming Zhou Zhen F.Fu Chengguang Zhang Ling Zhao 
the Guangdong Major Project of Basic and Applied Basic Research(2020B0301030007).
Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially availa...
关键词：Bordetella bronchiseptica Epidemiological investigation PATHOGENICITY IMMUNOGENICITY Inactivated vaccine 
Mycobacterium smegmatis enhances shikonin-induced immunogenic cell death—an efficient in situ tumor vaccine strategy被引量：1
《Journal of Biomedical Research》2024年第4期369-381,共13页Zhaoye Qian Zhe Zhang Lanqi Cen Yaohua Ke Jie Shao Manman Tian Baorui Liu 
supported by grants from the Natural Science Foundation of Huai'an Science and Technology Bureau(Grant No.HAB202312);the Science and Technology Development Fund of the Affiliated Hospital of Xuzhou Medical University(Grant No.XYFY2021018).
Tumor vaccines are a promising avenue in cancer immunotherapy.Despite the progress in targeting specific immune epitopes,tumor cells lacking these epitopes can evade the treatment.Here,we aimed to construct an efficie...
关键词：MYCOBACTERIUM SMEGMATIS SHIKONIN IMMUNOGENIC cell death tumor vaccines IMMUNOGENICITY CYTOTOXICITY 
全选清除导出
共27页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部