IMMUNOGENIC

作品数：60被引量：221H指数：8
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相关领域：医药卫生更多>>
相关作者：葛宜兵祁培培王锦红廖文婷潘卫更多>>
相关机构：第二军医大学更多>>
相关期刊：《World Journal of Immunology》《mLife》《Open Journal of Biophysics》《Asian Pacific Journal of Tropical Biomedicine》更多>>
相关基金：国家自然科学基金中国博士后科学基金World Health Organization更多>>
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Analysis of the Effects of Different Synthesis and Processing Methods on Circular RNA Integrity,Protein Expression,and Removal of Immunogenic Impurities
《Journal of Clinical and Nursing Research》2024年第9期191-200,共10页Shao Wang Tzuen Yih Saw Zebin Hong Kuo Chieh Liao Haiwei Song Yue Wan 
Circular RNAs(circRNAs)are emerging as a promising alternative to messenger RNAs(mRNAs)in gene delivery applications due to their enhanced stability and translation.Developing circRNA-based therapeutic platforms requi...
关键词：Nucleic acid therapeutics RNA manufacturing Circular RNA Gene delivery 
Dual inhibition of sirtuins 1 and 2:reprogramming metabolic energy dynamics in chronicmyeloid leukemia as an immunogenic anticancer strategy
《Cancer Communications》2024年第8期921-925,共5页Michael Schnekenburger Anne Lorant Sruthi Reddy Gajulapalli Ridhika Rajora Jin-Young Lee Aloran Mazumder Haeun Yang Christo Christov Hyoung Jin Kang Bernard Pirotte Marc Diederich 
LBMCC:“Recherche Cancer et Sang”foundation,the“Recherches Scientifiques Luxembourg”,the“Een Harz fir kriibskrank Kanner”,the Action LIONS“Vaincre le Cancer”and Télévie Luxembourg.SNU:National Research Foundation(NRF)(Grant Number 370C-20220063);MEST of Korea for Tumor Microenvironment Global Core Research Center(GCRC)(Grant Number 2011-0030001);Brain Korea(BK21)PLUS program and Creative-Pioneering Researchers Program at Seoul National University(Funding number:370C-20160062).Sruthi Reddy Gajulapalli and Ridhika Rajora were supported by grants for the“Graduate Scholarship for Excellent Foreign Students”program.
Chronicmyeloid leukemia(CML)is a lethal hematopoietic malignancy with a global incidence primarily attributed to the breakpoint cluster region-Abelson(BCR-ABL1)fusion oncogene in over 95%of cases.The introduction of t...
关键词：metabolism MYELOID alterations 
Mycobacterium smegmatis enhances shikonin-induced immunogenic cell death—an efficient in situ tumor vaccine strategy被引量：1
《Journal of Biomedical Research》2024年第4期369-381,共13页Zhaoye Qian Zhe Zhang Lanqi Cen Yaohua Ke Jie Shao Manman Tian Baorui Liu 
supported by grants from the Natural Science Foundation of Huai'an Science and Technology Bureau(Grant No.HAB202312);the Science and Technology Development Fund of the Affiliated Hospital of Xuzhou Medical University(Grant No.XYFY2021018).
Tumor vaccines are a promising avenue in cancer immunotherapy.Despite the progress in targeting specific immune epitopes,tumor cells lacking these epitopes can evade the treatment.Here,we aimed to construct an efficie...
关键词：MYCOBACTERIUM SMEGMATIS SHIKONIN IMMUNOGENIC cell death tumor vaccines IMMUNOGENICITY CYTOTOXICITY 
Preclinical Verification of Modulated Electro-Hyperthermia—Part III. Immunogenic Effects
《International Journal of Clinical Medicine》2024年第7期335-364,共30页Andras Szasz 
The modulated electro-hyperthermia (mEHT) method is a unique approach that utilizes all the essential apoptotic pathways through an external radiofrequency (RF) signal. The high-frequency RF is amplitude-modulated and...
关键词：mEHT Cancer Thermal Nonthermal IMMUNOGENIC ICD DAMP Tumor-Specific Immune 
Characterization of physicochemical and immunogenic properties of allergenic proteins altered by food processing:a review
《Food Science and Human Wellness》2024年第3期1135-1151,共17页Enning Zhou Qiangqiang Li Dan Zhu Gang Chen Liming Wu 
supported by the National Natural Science Foundation of China (32102605);the Agricultural Science and Technology Innovation Program under Grant (CAAS-ASTIP-2020IAR);the Earmarked Fund for CARS (CARS-44)。
Food allergens are mainly naturally-occurring proteins with immunoglobulin E(IgE)-binding epitopes.Understanding the structural and immunogenic characteristics of allergenic proteins is essential in assessing whether ...
关键词：Food allergens Protein structural characterization Immunogenicity evaluation Food processing modification 
Engineering nanomedicines for immunogenic eradication of cancer cells:Recent trends and synergistic approaches
《Acta Pharmaceutica Sinica B》2024年第6期2475-2504,共30页Ahmed O.Elzoghby Omar Samir Hagar E.Emam Ahmed Soliman Riham M.Abdelgalil Yomna M.Elmorshedy Kadria A.Elkhodairy Mahmoud L.Nasr 
Resistance to cancer immunotherapy is mainly attributed to poor tumor immunogenicity as well as the immunosuppressive tumor microenvironment(TME)leading to failure of immune response.Numerous therapeutic strategies in...
关键词：Immunogenic cell death Immunogenic eradication NANOMEDICINES Drug delivery Cancer immunotherapy Antitumor immunity T cells Tumor associated antigens Synergistic immune response 
Aspergillus niger prolyl endopeptidase in celiac disease
《World Journal of Gastroenterology》2024年第24期3044-3047,共4页Marica Colella Concetta Cafiero Raffaele Palmirotta 
We comment here on the article by Stefanolo et al entitled“Effect of Aspergillus niger prolyl endopeptidase in patients with celiac disease on a long-term gluten-free diet”,published in the World Journal of Gastroen...
关键词：Celiac disease Aspergillus niger prolyl endoprotease Gluten immunogenic peptides TRIAL SYMPTOMS Real-life trial 
A stepwise-responsive editor integrated with three copper ions for the treatment of oral squamous cell carcinoma
《Nano Research》2024年第6期5424-5434,共11页Jinna Ren Jingying Hu Fan Dong Yan Xu Yang Peng Yuping Qian Guanmeng Zhang Min Wang Yuguang Wang 
the National Key Research and Development Program of China(No.2022YFC2403203-3);Jilin Province Department of Finance(No.jcsz2023481-13);the National Natural Science Foundation of China(Nos.51972003 and 52271127);the Intergovernmental International Co-operation Project of Beijing Municipal Science and Technology Commission(No.Z221100002722004);the 2023 Management Research Project(No.YS040223).
Cuprotosis,a new type of cell death,provides great opportunities for the treatment of oral squamous cell carcinoma,as nanocarriers of copper ions can induce cuprotosis and immunogenic death.Here,we studied an editor t...
关键词：cuprotosis immunogenic death photothermal therapy tumor microenvironment IMMUNOTHERAPY 
Radiation-based immunogenic vaccine combined with a macrophage“checkpoint inhibitor”for boosting innate and adaptive immunity against metastatic colon cancers
《Acta Pharmaceutica Sinica B》2024年第5期2247-2262,共16页Hongbo Xu Xianya Qin Yuanyuan Guo Siyu Zhao Xingxing Feng Runzan Zhang Tianyi Tian Li Kong Conglian Yang Zhiping Zhang 
This research was supported by the National Natural Science Foundation of China(No.82104098,China);the Program for HUST Academic Frontier Youth Team(No.2018QYTD13,China);Wuhan Science and Technology Plan(2022023702025187,China);Natural Science Foundation of Hubei Province(2023AFD152,China).
Immunogenic dying tumor cells hold promising prospects as cancer vaccines to activate systemic immunity against both primary and metastatic tumors.Especially,X-ray-induced dying tumor cells are rich in highly immunoge...
关键词：Immunogenic cell death Cancer vaccine X-ray EFFEROCYTOSIS MACROPHAGE STING Adaptive immunity Innate immunity 
Pan-cancer immunogenic death analysis identifies key roles of CXCR3 and CCL18 in hepatocellular carcinoma
《Genes & Diseases》2024年第2期568-570,共3页Jia Guo Xin Sun Guowei Pan Ce Li Xin He Xiaofang Che Zan Teng Xiujuan Qu Yunpeng Liu Bowen Yang 
Immunogenic death is a form of programmed cell death that is common in the development and progression of cancer.However,its impact on tumor progression differs depending on the location of the tumor.Meanwhile,it also...
关键词：DEATH CXCR3 IMMUNITY 
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