云南高校图书馆联盟文献共享服务平台- SMEGMATIS

SMEGMATIS: 作品数：12被引量：17H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：高世同陈雅棠吴少庭郑春福林敏更多>>; 相关机构：广东省妇幼保健院重庆医科大学附属第一医院深圳市卫生防疫站中国药品生物制品检定所更多>>; 相关期刊：《Advances in Enzyme Research》《Advances in Microbiology》《分析化学》《Journal of Biomedical Research》更多>>; 相关基金：国家自然科学基金国家教育部博士点基金更多>>

Mycobacterium smegmatis enhances shikonin-induced immunogenic cell death—an efficient in situ tumor vaccine strategy被引量：1: 《Journal of Biomedical Research》2024年第4期369-381,共13页Zhaoye Qian Zhe Zhang Lanqi Cen Yaohua Ke Jie Shao Manman Tian Baorui Liu; supported by grants from the Natural Science Foundation of Huai'an Science and Technology Bureau(Grant No.HAB202312);the Science and Technology Development Fund of the Affiliated Hospital of Xuzhou Medical University(Grant No.XYFY2021018).; Tumor vaccines are a promising avenue in cancer immunotherapy.Despite the progress in targeting specific immune epitopes,tumor cells lacking these epitopes can evade the treatment.Here,we aimed to construct an efficie...; 关键词：MYCOBACTERIUM SMEGMATIS SHIKONIN IMMUNOGENIC cell death tumor vaccines IMMUNOGENICITY CYTOTOXICITY

GP30 of the mycobacteriophage CASbig impairs mycobacterial adaptation during acidic stress and in macrophages: 《BIOCELL》2020年第4期695-701,共7页WU LI JIANGZHE SI SHUAI QIU JING LUO HUIQIONG SUN XIAOQING LI ZHIBIN WAN WEI GAO HANLU ZOU LEI ZHANG XIAOHONG XIANG YANZHANG LI TIESHAN TENG; Key R&D and Promotion Projects of Henan Province,grant number 192102310156,the National Natural Science Foundation of China,Grant No.81601740;the Applied Basic Research Program of Science&Technology Department of Sichuan Province,Grant No.2018JY0108;the National Undergraduate Training Program for Innovation and Entrepreneurship(X2017013,X2019070,202010475006).; The rapid emergence of multidrug-resistant and extensively drug-resistant Tuberculosis retrieved intense interest in phage-based therapy.This old approach,which was abandoned in the west in the 1940s but is generating...; 关键词：MYCOBACTERIUM SMEGMATIS gp30 CASbig ACIDIC STRESS Macrophage

Efficient circular gene knockout system for Burkholderiales strain DSM 7029 and Mycobacterium smegmatis mc^2 155被引量：3: 《Acta Biochimica et Biophysica Sinica》2019年第7期697-706,共10页Xiaolai Lei Qiuxia Fan Tian Huang Haiyun Liu Guoping Zhao Xiaoming Ding; Multiple gene knockouts are often employed in studies of microbial physiology and genetics. However, the selective markers that confer antibiotic resistance are generally limited, so it is necessary to remove these re...; 关键词：serine INTEGRASE multiple gene KNOCKOUTS Burkholderiales STRAIN DSM 7029 Mycobacterium SMEGMATIS

基于MspA蛋白质纳米孔传感器的主客体化学研究被引量：4: 《分析化学》2016年第12期1801-1807,共7页段静卓莎姚付军张亚妮亢晓峰; 国家自然科学基金(Nos.21175105;21375104;21327806);教育部博士点基金(No.20126101110015)资助~~; 以大肠杆菌原核系统表达的方法制备了MspA蛋白质纳米孔,并利用表面活性剂高温提取获得高活性MspA蛋白纳米孔。实验结果表明,0.5%的提取剂90℃提取30 min为最佳提取条件。利用制备的MspA纳米孔在单分子水平上研究了其与多种环糊精的相互...; 关键词：MYCOBACTERIUM SMEGMATIS PORIN A 纳米通道单分子检测环糊精盐酸金刚烷胺

Disruption of <i>Mycobacterium smegmatis</i>Biofilms Using Bacteriophages Alone or in Combination with Mechanical Stress: 《Advances in Microbiology》2015年第10期699-710,共12页Brendan Kiefer John L. Dahl; Environmental mycobacteria are capable of forming biofilms in low-nutrient environments, and these biofilms may act as reservoirs for opportunistic infections. The purpose of this study was to determine if bacteriopha...; 关键词：Mycobacterium SMEGMATIS Biofilm MYCOBACTERIOPHAGE BACTERIOPHAGE

Screening of Several Anti-Infectives for in Vitro Activity against Mycobacterium smegmatis: 《Advances in Microbiology》2014年第16期1197-1203,共7页Grace Lovia Allotey-Babington Henry Nettey Philip Debrah Ofosua Adi-Dako Clement Sasu Anastasia Antwi Yvonne Darko Newriza Nartey Jida Asare; Aim: To evaluate in vitro the effectiveness of several anti-infective agents alone or in combination against Mycobacterium smegmatis. Method: A convenient stratified sampling method was used to obtain selected anti-in...; 关键词：Antimicrobials Minimum INHIBITORY Concentration M. SMEGMATIS TUBERCULOSIS

Cloning and Expression of a Novel Phytase Gene (phyMS) from <em>Mycobacterium smegmatis</em>: 《Advances in Enzyme Research》2014年第1期27-38,共12页Tamrin Nuge Yumi Zuhanis Has-Yun Hashim Abd-El Aziem Farouk Hamzah Mohd Salleh; Phytase, also known as phytate-degrading enzyme, catalyzes the hydrolysis of phytate (inositol hexakisphosphate) with sequential release of phosphate and lower inositol phosphate. We report here a new plasmid construc...; 关键词：MYCOBACTERIUM SMEGMATIS Thermostability PHYTASE BROAD pH Activity BROAD Substrate

Recombinant Mycobacterium smegmatis expressing Hsp65-hIL-2 fusion protein and its influence on lymphocyte function in mice被引量：1: 《Asian Pacific Journal of Tropical Medicine》2012年第5期347-351,共5页Xiao-Qing Guo Yan-Ming Wei Bo Yu; funded by the National Natural Science Eoundation of China(Grant ID:30972767); Objective:To coastruct a strain of recombinant Mycobacterium smegmatis expressing the heat shock protein 65(Hsp65) and human interleukin 2(IL-2) fusion protein(rMS-Hsp65/IL-2) and to explore the effect of this constru...; 关键词：MYCOBACTERIUM tuberculosis MYCOBACTERIUM SMEGMATIS HSP65 IL-2 Fusion protein Lymphocytes MICE

无细胞M.Smegmatis菌苗的研究与应用: 《中国防痨杂志》2002年第z1期1-2,共2页徐苗陈保文沈小兵苏城王国治; 　　结核病是世界卫生组织(WHO)公布的危害人类健康的十大疾病之一.我国目前同样面临结核病的严峻挑战,2000年全国结核病流行病学调查结果表明,我国目前有近半人口(约5.5亿)感染了结核菌,其中有5000多万人为结核菌素实验强反应者(硬结...; 关键词：菌苗动物模型免疫功能疫苗 M.Smegmatis 卡介苗结核菌苗无细胞亚细胞结核菌感染结核病豚鼠荷兰猪

恶性疟原虫FCC-1/HN株裂殖子表面抗原2基因在M.smegmatis mc^2155中的表达被引量：5: 《中华微生物学和免疫学杂志》2001年第5期531-534,共4页郑春福吴少庭陈雅棠高世同林敏梁驹卿; 目的　研究裂殖子表面抗原 2 (merozoitesurfaceantigen 2 ,MSA2 )基因重组BCG疫苗的保护作用。方法　采用电穿孔转化法将重组质粒pBCG/MSA2导入耻垢分枝杆菌 (M .smegmatis)mc2 1 55中 ,通过卡那霉素抗性筛选并经PCR鉴定的重组M .smegm...; 关键词：恶性疟原虫耻垢分枝杆菌基因表达裂殖子表面抗原2 穿梭质粒

SMEGMATIS