^(125)I粒子植入在治疗晚期肝癌中的应用  

^(125)I seeds implanted in the treatment of advanced hepatocellular carcinoma

作　　者：牛省利 牛丽林 范存雷 黄娟[3] 

机构地区：[1]河南省平顶山市第一人民医院消化科,467000 [2]河南省平顶山市第一人民医院影像科,467000 [3]河南省平顶山市第一人民医院妇产科,467000

出　　处：《中国实用医药》2012年第29期26-27,共2页China Practical Medicine

摘　　要：目的评价CT引导下125I粒子植入术在治疗晚期肝癌中疗效。方法对15个肝癌病灶行CT引导下125I粒子植入,在CT引导下穿刺植入125I粒子。植入术后立即及术后3～6个月行CT扫描观察粒子在瘤体内的分布、有无并发症发生及疗效。结果单个肝癌病灶内植入125I粒子数为8～55粒(平均24.4粒)。未出现急性并发症和与放射损伤。CT检查示2个病灶消失,13个病灶明显缩小。植入术前及植入术后病灶直径平均值(cm)分别为4.31±1.80和1.15±0.62(t=6.43,P<0.05)。结论 CT引导下瘤体内125I粒子植入近距离放射治疗对晚期肝癌的近期治疗效果满意。Objective To evaluate efficacy of CT-guided intratumoral 125I seeds implantation for ad- vanced hepatoeellular carcinoma. Methods Nine patients with 15 tumors by CT-guided next intratumoral 125I seeds implantation, CT guided implantation of 125 I particles. Implant immediately after surgery 3 ~ 6 months CT scan was observed particle distribution in tumor tissue, with or without complications and efficacy. Results Nine patients with seed implantation were successfully completed, satisfied with the particle distribution, a sin- gle intratumoral implantation of 1251 number of particles of 8 ~ 55 particles （ average 24. 4）. No acute complica- tions and treatment of radiation injury. CT scan showed two lesions disappeared, 13 lesions were significantly reduced. Implantation before and after implantation of lesions with average diameter （cm） were 4. 31 ± 1.80 and 1.15 ± 0. 62 （ t = 6. 43, P 〈 0. 05 ）. Conclusion CT-guided tumor in vivo of 125I seed implantation brachytherapy for the satisfaction of the recent treatment of advanced hepatocellular carcinoma.

关 键 词：晚期肝癌 碘放射性同位素 近距离放射疗法 

分 类 号：R735.7[医药卫生—肿瘤]