PACG激光虹膜切开术前后前节OCT扫描各参数变化研究  

Comparison of anterior segment changes before and after laser peripheral iridotomy by anterior segment optical coherence tomography in eyes with primary angle-closure glaucoma

作　　者：庄晓彤[1] 王凤敏[2] 肖伟[3] 

机构地区：[1]中国辽宁省沈阳市第四人民医院眼科,110031 [2]中国辽宁省沈阳市第五人民医院眼科,110023 [3]中国医科大学附属盛京医院眼科,中国辽宁省沈阳市110001

出　　处：《国际眼科杂志》2012年第11期2151-2153,共3页International Eye Science

摘　　要：目的:观察原发性闭角青光眼(primary angle closure glaucoma,PACG)行激光虹膜切开术前后前节OCT扫描参数变化。方法:原发性闭角型青光眼30例42眼1/2以上象限房角开放,进行自身对照研究,利用前节OCT于激光虹膜切开术前及术后4wk进行检查,主要指标包括:前房角开放距离、小梁网与虹膜间面积、中央前房深度。术前术后检测参数比较,服从正态分布采用配对t检验,不服从正态分布的采用秩和检验。结果:PACG患者30例42眼LPI术前距巩膜突500μm处,前房角开放距离0.172±0.078μm,小梁网与虹膜间面积0.066±0.025mm2;距巩膜突750μm处,前房角开放距离0.268±0.133μm,小梁网与虹膜间面积0.122±0.045mm2;LPI术后距巩膜突500μm处,前房角开放距离0.277±0.105μm,小梁网与虹膜间面积0.113±0.041mm2;距巩膜突750μm处,前房角开放距离0.388±0.154μm,小梁网与虹膜间面积0.194±0.063mm2(P<0.05)差异有统计学意义,但前房深度无明显变化,差异无统计学意义(P=0.108)。结论:激光虹膜切开术可以解决瞳孔阻滞,使前房角开放距离、小梁网与虹膜间面积增加,但前房深度不变。AIM：To evaluate the changes of anterior segment configuration after laser peripheral iridotomy（LPI） in patients with primary angle-closure glaucoma（PACG） by using anterior segment optical coherence tomography（AS-OCT）.METHODS：This retrospective self control study consisted of forty-two eyes of 30 patients with PACG whose open angles were more than 180 degree.Central anterior chamber depth（ACD）,opening distance（AOD）,trabecular iris area（TISA） were measured using AS-OCT before and four weeks after LPI.RESULTS：：The parameters of AS-OCT on baseline were AOD 0.172±0.078μm,TISA 0.066±0.025mm2 at 500μm anterior to sclera spur,and AOD 0.268±0.133μm,TISA 0.122±0.045mm2 at 750μm.After LPI,the parameters were AOD 0.277±0.105μm,TISA 0.113±0.041mm2 at 500μm,and AOD 0.388±0.154μm,TISA 0.194±0.063mm2 at 750μm,which were significantly increased compared with the baseline（P0.05）.There was no significant difference on ACD before and after LPI（P=0.108）.CONCLUSION：PACG can be controlled by LPI resulting in an increase of AOD,TISA but not ACD.

关 键 词：眼前段 光学相干 激光虹膜切开术 原发性闭角青光眼 前房深度 

分 类 号：R779.6[医药卫生—眼科]