自体带Bruch膜视网膜色素上皮复合体移植术后早期眼压观察  

Early postoperative intraocular pressure of transplantation of autologous retinal pigment epithelium-Bruch membrane complex

作　　者：安刚[1] 王友[1] 李雪[1] 李林[1] 

机构地区：[1]辽宁医学院附属锦州市中心医院眼科中心,中国辽宁省锦州市121001

出　　处：《国际眼科杂志》2012年第11期2157-2159,共3页International Eye Science

摘　　要：目的:探讨联合自体视网膜色素上皮与Bruch膜复合体移植术后早期的眼压变化情况。方法:选择24例25眼黄斑区域视网膜下较大面积出血的年龄相关性黄斑变性(ARMD)患者分A,B两组,A组为行常规玻璃体切割、黄斑下出血和脉络膜新生血管膜(CNV)取出术联合硅油填充术患者,B组在A组手术方式基础上联合自体视网膜色素上皮与Bruch膜复合体移植。以Goldmann眼压仪为测量工具,记录各组患者手术前1d眼压,以及术后第1wk每天上午眼压情况,对结果进行统计处理并分析其可能原因。结果:A组患者手术眼术后第1,2d眼压及术后第1wk平均眼压、峰值眼压、高眼压发生率低于B组,其差异均具有统计学上的意义(P<0.05),而术后第1wk内其它各天的A,B两组手术眼眼压无显著差异。结论:对于黄斑区域视网膜下较大面积出血的ARMD,行联合自体视网膜色素上皮与Bruch膜复合体移植术较单纯行黄斑下出血和CNV取出术术后早期的眼压值及高眼压发生率略高,注意在围手术期内预防高眼压。AIM：To observe the early postoperative intraocular pressure（IOP） of transplantation of autologous retinal pigment epithelium（RPE）-Bruch membrane complex after the removal of corneal neovascularization（CNV）.METHODS：A retrospective study was performed in 24 patients 25 eyes with age-related macular degeneration（ARMD） who underwent vitreoretinal surgery and related literatures were reviewed.The 24 patients 25 eyes were divided to group A（the macular subretinal hemorrhage and CNV removal surgery group,n=14） and group B（transplantation of autologous RPE-Bruch membrane complex after the removal of the CNV group,n=11）.IOP was measured before surgery and then on day 1,2,3,4,5,6 and 7 after surgery with Goldmann applanation tonometer.Two sets of IOP were counted and possible factors were analyzed for association with ocular hypertension.RESULTS：：The IOP was elevated on day 1 after surgery in 78.1% of all cases,and also elevated significantly on day 2 in 56.4% of group B,respectively.Besides,the mean postoperative IOP,the peak postoperative IOP and incidence of high IOP at week 1 was elevated significantly in group B,respectively.CONCLUSION：Early postoperative IOP and incidence of high IOP in patients with hemorrhagic ARMD undergoing transplantation of autologous RPE-Bruch membrane complex after the removal of the CNV have significant elevation,and need for perioperative prevention of high IOP should be noted.

关 键 词：高眼压 玻璃体视网膜手术 术后并发症 

分 类 号：R779.6[医药卫生—眼科]