骨修复复合材料及其相关问题的研究进展  

Advances in Bone Repair Composite Materials and Related Issues

作　　者：廖世波[1] 赖琛[2] 张志雄[2] 盛立远[2] 奚廷斐[1,2] 

机构地区：[1]温州医学院信息与工程学院,温州325035 [2]北京大学深圳研究院生物医学工程研究中心,深圳518057

出　　处：《中国生物医学工程学报》2012年第5期755-761,共7页Chinese Journal of Biomedical Engineering

基　　金：国家重大科学研究计划项目(2012CB933603);浙江省新苗人才计划项目(2012R413046);深圳市科技计划项目(JC200903170498A)

摘　　要：寻找理想的骨修复材料一直是骨组织工程领域的研究热点之一。本文对近5年来骨修复复合材料及其相关问题的研究进展进行综述。首先简述了骨修复复合材料的研究现状,其中包括纳米复合材料、负载活性因子的复合材料、引入基因工程的复合材料、磁性复合材料。然后对骨组织工程材料的血管化问题进行了较为深入的探讨。最后指出了目前骨修复复合材料存在的问题,并对其进行了前景展望。To explore ideal materials for bone repair is one of the hot topics in the field of bone tissue engineering. In this paper, research progress on bone regeneration composite materials and related issues in the last five years were reviewed. We described the present research status of bone repair composite materials including nanocomposites, composite materials loaded with active factors, composite materials introduced genetic engineering, magnetic composite materials. Discussion in - depth for vascularization of bone tissue engineering materials was also given in the article. Meanwhile, problems existing in bone regeneration composites were pointed out while its prospect was also proposed.

关 键 词：纳米复合材料 基因工程 生长因子 磁性粒子 血管化 

分 类 号：R318.08[医药卫生—生物医学工程]