重复经颅磁刺激对首发抑郁症患者治疗作用的临床分析  

Clinical Analysis of Therapeutic Effects on Repetitive Transcranial Magnetic Stimulation in First- Episode Patients with Major Depressive Disorders

作　　者：李金贤[1] 莫煊[2] 马瑞[2] 

机构地区：[1]新疆维吾尔自治区人民医院康复医学科,新疆乌鲁木齐830001 [2]新疆维吾尔自治区人民医院临床心理科,新疆乌鲁木齐830001

出　　处：《新疆医学》2012年第10期33-35,共3页Xinjiang Medical Journal

摘　　要：目的:探讨重复经颅磁刺激对首发抑郁症的患者治疗作用。方法:36例首发抑郁症患者随机分为两组:假刺激+抗抑郁药物组;重复经颅磁刺激+抗抑郁药物组;重复经颅磁刺激(rTMS)治疗4周,每周5次,10天为一疗程。结果:经重复经颅磁刺激(rTMS)组患者的HDRS和BDI在治疗1周末(t=-8.58和8.52,P<0.05),2周末(t=4.28和5.09,P<0.05),4周末(t=5.22和7.94,P<0.05)较对照组有显著的统计学差异。结论:rTMS+抗抑郁剂用于首发抑郁症患者可加快起效速度,从而增加此类患者治疗依从性。Objective;To explore the effect of repetitive transcranial magnetic stimulation on first - episode Depression.Methods：36 patients with first - onset depression were randomly divided into pseudo magnetic stimulation group and repetitive transcranial magnetic stimulation treatment groups.Use this treatment five a day for 4 weeks and lOdays for a course.Results;The scores of Hamilton Depression Scale and Beck Depression Scale have significantly reduced in the first week（t =8.58 and 8.52.P 0.05）.second week（t =4.28 and 5.09,P 0.05） and forth week（t = 5.22 and 7.94,P 0.05 ） of rTMS treatment.There is significant difference between pseudo magnetic stimulation group and repetitive transcranial magnetic stimulation treatment group.Conclusion rTMS treatment can improve the efficacy and compliance of anti - depression therapy.It is still necessary to continue to take drugs for maintaining the effect alter stopping rTMS treatment,in first - episode patients with major depressive disorders.

关 键 词：抑郁 重复经颅磁刺激 汉密尔顿抑郁量表 Beck自评抑郁问卷 

分 类 号：R742.5[医药卫生—神经病学与精神病学]