纳米碳颗粒定位法在腹腔镜结肠癌手术中的应用  

Application of Preoperative Colonoscopic Tattooing Using Carbon Nanoparticles for Localization in Laparoscopic Colonic Surgery

作　　者：陈翀[1] 李权[1] 张筱骅[1] 胡孝渠[1] 

机构地区：[1]温州医学院附属第一医院肿瘤外科,325000

出　　处：《医学研究杂志》2012年第10期113-115,共3页Journal of Medical Research

摘　　要：目的评价纳米碳标记肿瘤在腹腔镜结肠癌手术中的应用前景。方法在2009年7月～2011年7月选取65例结肠癌手术病人。取31例经肠镜注射纳米碳颗粒悬液定位肿瘤位置,其他34例未处理做阴性对照。结果在所有标记的病人中标记定位处染色明显清楚,病人没有腹痛、发热、腹泻等症状。统计两组患者的术中确定病灶时间、手术时间和术中出血量,发现有明显差别,且有统计学意义(P<0.01或0.05)。结论纳米碳标记在腹腔镜结肠手术中安全且有效。Objective To evaluate the effectiveness of tattooing colonic neoplasms with carbon nanoparticles in laparoscopic colonic cancer surgery. Methods From July 2009 to July 2011 , 65 patients with colonic carcinomas were recruited and divided as experimental group （ n = 31 ） and control group （ n = 34）. The patients in the experimental group were localized preoperatively by endoscopic carbon nanoparticles tattooing, while those in the control group were no tattooed. Results All the injection sites were visible to the surgeons in 31 cases. None of 65 patients had abdominal pain, fever, diarrhoea or any other symptoms of inflammation development. There were significant differences in the time of finding neoplasms, operative time and hemorrhage amount of the patients during the operation between two groups （ P 〈 0.05 ）. Conclusion Tattooing colonic neoplasms with carbon nanoparticles in laparoscopic colonic cancer surgery is safe and useful.

关 键 词：结肠镜 腹腔镜 结肠癌 纳米碳颗粒 标记 

分 类 号：R735.35[医药卫生—肿瘤]