EB病毒与淋巴瘤相关性的研究进展  

Research progress on EB virus and its associated lymphoma

作　　者：黄小银(综述)[1] 王靖华(审校)[1] 

机构地区：[1]南京大学医学院临床学院、南京军区南京总医院肿瘤内科,南京210002

出　　处：《临床肿瘤学杂志》2012年第10期951-954,共4页Chinese Clinical Oncology

摘　　要：EB病毒(EBV)是一种γ-疱疹病毒,与伯基特淋巴瘤、霍奇金淋巴瘤、NK/T细胞淋巴瘤及移植后淋巴组织增殖性疾病等密切相关。研究表明,EBV潜伏感染的基因表达产物对淋巴瘤的发生起到了促进作用,并为EBV相关淋巴瘤免疫治疗提供了依据。本文主要就EBV、EBV潜伏感染基因表达产物及其相关淋巴瘤的研究进展作一综述。Epstein-Barr virus（EBV） is a γ-herpesvirus,is associated with Burkitt＇s lymphoma, Hodgkin＇s disease, NK/T cell lymphoma and post-transplant lymphoproliferative disorder. Researchs have shown that the gene products of latent infection of EBV pro- mote the occurrence of the lymphoma. These researchs have also provided the reason for immune therapy in regard to EBV. This review mainly discuss the research progress about the EBV, the gene products of latent infections of EBV and the relationship between lymphoma and EBV.

关 键 词：EBV 淋巴瘤 基因表达产物 潜伏感染 治疗 

分 类 号：R730.51[医药卫生—肿瘤]