镍铬合金烤瓷冠对人体尿中镍、铬离子的影响  

Effect of nickel chromium alloy porcelain-fused-metal crown on the nickel and chromium ion concentration in human urine

作　　者：吐尔洪阿依.塔西甫拉提 王星[1] 何惠宇[1] 

机构地区：[1]新疆医科大学第一附属医院口腔修复科,新疆维吾尔自治区乌鲁木齐市830054

出　　处：《中国组织工程研究》2012年第38期7078-7082,共5页Chinese Journal of Tissue Engineering Research

摘　　要：背景:镍铬合金烤瓷冠因其机械性能优良、低廉价格,在国内口腔修复领域广泛应用。目的:观察镍铬合金烤瓷冠对患者尿中镍、铬离子的量的影响。方法:选择2009-03/2010-03在新疆医科大学第一附属医院就诊戴用镍铬合金烤瓷冠患者55例为实验组,同期未做任何修复治疗者55例为对照组,比较2组患者尿中镍、铬的离子水平。结果与结论:镍铬合金冠修复患者尿镍、铬离子水平与对照组接近(P>0.05),且镍铬合金烤瓷冠数量<5个与≥5个的患者的镍、铬离子水平也接近(P>0.05),但与使用镍铬合金烤瓷冠<5年的患者相比,使用年限≥5年者的尿镍、尿铬离子水平升高(P<0.05,P<0.01)。提示镍铬合金烤瓷冠修复不会影响患者尿中镍、铬离子水平,但镍铬合金烤瓷冠使用年限会影响患者尿中的镍、铬离子的水平。BACKGROUND：Nickel chromium alloy porcelain-fused-metal crown has been widely used in the field of domestic prosthodontics as its excellent mechanical properties and low price.OBJECTIVE：To observe the influence of the nickel chromium alloy porcelain crowns on the concentration of nickel and chromium ions in patients＇ urine.METHODS：The patients were selected from the First Affiliated Hospital of Xinjiang Medical University from March 2009 to March 2010.Fifty-five patients with nickel chromium alloy porcelain-fused-metal crown were as the experimental group,and 55 patients without any treatment were as the control group,then the nickel and chromium levels in urine were compared between two groups.RESULTS AND CONCLUSION：Urinary nickel and chromium levels of the experimental group were similar to those of the control group （P 0.05）,and the nickel and chromium levels of the patients with nickel chromium alloy porcelain crowns 5 were similar to those of the patients with nickel chromium alloy porcelain crowns ≥ 5 （P 0.05）.But compared with the patients with nickel chromium alloy porcelain crowns 5 years,the urinary nickel and chromium levels of the patients with nickel chromium alloy porcelain crowns ≥ 5 were increased （P 0.05）.Nickel-chromium alloy porcelain crown restoration cannot affect the urinary nickel and chromium levels,but the length of nickel chromium alloy porcelain crown wearing can affect urinary nickel and chromium levels.

关 键 词：镍铬合金烤瓷冠 尿镍 尿铬 不良反应 口腔修复 口腔材料 生物材料 组织工程 

分 类 号：R318[医药卫生—生物医学工程]