脑梗死后出血转化危险因素的相关性研究  

Correlative study of risk factors for hemorrhagic transformation after cerebral infarction

作　　者：刘慧[1] 谢明[1] 

机构地区：[1]南华大学附属第一医院神经内科,湖南衡阳421001

出　　处：《中国当代医药》2012年第30期53-54,共2页China Modern Medicine

摘　　要：目的探讨脑梗死后出血转化与脑微出血及其他危险因素的相关性。方法回顾性分析2009年10月～2011年12月,本院492例脑梗死患者的临床资料,将其分为HT组(62例)和非HT组(430例),分析两组中脑微出血(CMB)、抗凝治疗、高血压、大面积的梗死、年龄、吸烟、酗酒等指标是否有差异,从而确定HT与CMB等危险因素的相关性。结果统计分析采用χ2检验,结果显示梗死后出血转化与CMB、高血压、大面积梗死、溶栓抗凝治疗有一定的相关性,差异有统计学意义(P<0.05),而与另外几项危险因素:年龄、吸烟、酗酒HT组与非HT组间没有较大差别,差异无统计学意义(P>0.05)。结论 CMB、高血压、大面积梗死、溶栓抗凝治疗可能是梗死后出血转化的危险因素。Objective To investigate the relationship between hemorrhagic transformation （HT） after acute ischemic infarction and cerebral micro bleeds （CMB） or other related risk factors.Methods Four hundred and ninety-two cases with acute infarction from October 2009 to December2011 in our hospital were divided into HT and non-HT groups,The differences of CMB,anticoagulant therapy,hypertension,a large area of infarction,age,smoking,alcoholism and other indicators were analysed in both groups,so that the correlation between these risk factors with HT could be determined.Results X-test results showed that the HT group was correlation with the CMB,high pressure,a large area of infarction,thrombolytic and anticoagulant therapy （P0.05）,while there was little differences between the HT group and the non-HT group in the following indicators：age,smoking,alcoholism （P0.05）.Conclusion CMB,high pressure,a large area of infarction,thrombolytic anticoagulant therapy are possible risk factors of HT after acute ischemic infarction.

关 键 词：脑梗死 出血转化 危险因素 相关性研究 

分 类 号：R743[医药卫生—神经病学与精神病学]