复发恶性脑胶质瘤患者25例调强适形放射治疗后的生存质量分析  

Quality of life after intensity modulated radiotherapy for 25 cases of recurrent malignent gliomas

作　　者：王权[1] 李良[2] 韩倩[2] 刘海龙[1] 

机构地区：[1]河南省肿瘤医院放疗科,郑州450003 [2]河南省人民医院放疗科

出　　处：《临床医学》2012年第10期22-23,共2页Clinical Medicine

摘　　要：目的评价采用调强适形放射治疗(IMRT)技术再程放疗复发恶性脑胶质瘤患者的生存质量。方法根据EORTC QLQ-C30量表调查25例复发恶性脑胶质瘤患者接受再程常规分割放射治疗的生存质量。结果患者IMRT后的躯体功能、角色功能、认知功能维持在IMRT前的稳定水平(P>0.05),总体健康状况较前好转(P<0.05)。患者IM-RT后的疲倦和疼痛症状维持在IMRT前的水平(P>0.05),恶心/呕吐症状有所减轻(P<0.05)。结论 IMRT再程放疗对复发恶性脑胶质瘤患者安全、有效。Objective To evaluate the quality of life in patients with recurrent malignant gliomas with intesity modulated radi- aotherapy（IMRT）. Methods From February 2006 to March 2010, 25 patients with recurrent gliomas were re-irradiated with conventional fractional IMRT. Quality of life was evaluated using the EORTC QLQC-30. Results The physical function, role function, cognitive function were stable（ P 〉 0.05 ） , global quality of life was better than before（ P 〈 0.05 ）. Fatigue and pain were stable（ P 〉 0.05 ）, nause/vomiting were relieved（ P 〈 0.05 ）. Conclusion Re-irradiation with IMRT for recurrent ma- lignant gliomas is effective and safe.

关 键 词：胶质瘤 放射治疗 复发 生存质量 

分 类 号：R739.4[医药卫生—肿瘤]