胃癌行全胃切除术76例临床疗效分析  

Clinical analysis of total gastrectomy for gastric cancers:report of 76 cases

作　　者：桑温昌[1] 李兆德[1] 张军[1] 赵迎春[1] 王新征[1] 

机构地区：[1]济南市槐荫人民医院普通外科,250021

出　　处：《中华普外科手术学杂志（电子版）》2012年第4期13-16,共4页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

摘　　要：目的探讨在行全胃切除术的胃癌患者中保留迷走神经的可行性及临床效果。方法选择76例行全胃切除术的胃癌患者,其中41例患者术中保留迷走神经作为观察组;随机选择35例未保留迷走神经的全胃切除术患者作为对照组,比较两组患者术后的肠功能恢复、营养状况、进食情况及术后并发症发生率。结果观察组患者术后肠道恢复较对照组患者快,住院日期短,较少出现返流、腹泻等症状(P<0.05);术后6个月及1年单餐进食量及血清营养指标相比,观察组患者明显优于对照组。两组患者在术后并发症发生率、死亡率相比较,差异无统计学意义(P>0.05)。结论在迷走神经未被侵及的胃癌患者中迷走神经可予以保留,该术式能提高胃癌患者术后的生活质量,防止术后消化功能紊乱。Objective To investigate the feasibility and outcome of total gastrectomy with preserved vagus nerve in patients with gastric cancer.Methods In the observation group,41 patients received total gastrectomy with preserved vagus nerve,while 35 patients received total gastrectomy with severed vagus nerve who served as controls.The postoperative recovery of gastrointestinal function,nutritional parameters,food intake and complications were compared between the two groups.Results The data of the patients showed that intestinal function recovered earlier with less postoperative complications（such as reflux and diarrhea） and shorter hospital stay in the observation group than in the control group（P0.05）.Compared with the control group,the food intake volume in a single meal and serum nutrition were improved in the patients with preserved vagus never in the observation group.Postoperative morbidity and mortality were similar between the two groups（P0.05）.Conclusions It is feasible to preserve the vagus never in patients with gastric cancer and without nerval lesion when total gastrectomy is performed.Total gastrectomy with preserved vagus nerve could improve the quality of life and prevent digestive disorder in patients with gastric cancer.

关 键 词：胃肿瘤 胃切除术 迷走神经切断术 可行性研究 治疗效果 

分 类 号：R735.2[医药卫生—肿瘤]