镍钛拉簧和弹力橡皮链关闭拔牙间隙有效性和安全性的Meta分析  

Effectiveness and Safety of Power Chain versus Nickel Titanium Coil Springs in Closing Dental Extraction Space:A Meta-Analysis

作　　者：陈燕[1] 舒维娜 何等旗[1] 

机构地区：[1]兰州大学第一医院口腔科,兰州730000 [2]甘肃省兰州市口腔医院,兰州730000

出　　处：《中国循证医学杂志》2012年第11期1391-1395,共5页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价镍钛拉簧和弹力橡皮链关闭拔牙间隙的有效性和安全性。方法计算机检索PubMed、EMbase、The Cochrane Library、CBM、CNKI和VIP,检索时限截至2012年2月,查找以上述两种方式关闭拔牙间隙的RCT。由两位研究者按照纳入与排除标准独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用RevMan 5.0软件进行Meta分析。结果共纳入4个RCT,122例患者。Meta分析结果显示:镍钛拉簧和弹力橡皮链在关闭拔牙间隙速度上差异有统计学意义[MD=0.30,95%CI(0.17,0.44),P<0.000 1];亚组分析提示,无论是方法学质量较高亚组[MD=0.20,95%CI(0.07,0.34),P=0.003]还是方法学质量较低亚组[MD=0.40,95%CI(0.30,0.50),P<0.000 01],两组在关闭拔牙间隙速度方面差异均有统计学意义。结论当前临床证据表明,镍钛拉簧在关闭拔牙间隙速度方面优于弹力橡皮链,但其远期效果尚需更大样本的随机对照试验进一步验证。Objective To systematically review the effectiveness and safety of power chain vs. nickel titanium coil springs in closing dental extraction space. Methods Databases including PubMed, EMbase, The Cochrane Library, Chinese Biomedicine Literature Database, Chinese Scientific Journals Full-text Database, and Chinese Journal Full-text Database were searched to collect the randomized controlled trials （RCTs） on comparing power chain with nickel tita- nium coil springs published before February 2012. Two reviewers independently screened literature, extracted data and assessed the quality of the included studies. Then meta-analysis was conducted using RevMan 5.0 software. Results A total of 4 RCTs involving 122 patients were included. The results of meta-analyses showed that there was a significant dif- ference in the rate of space closure between the two groups （MD=0.30 mm per month, 95%CI 0.17 to 0.44, P〈0.000 1）; The results of subgroup analyses indicated that, both high-quality trials （MD=0.20, 95%CI 0.07 to 0.34, P=0.003） and low quality trials （MD=0.40, 95%CI 0.30 to 0.50, P〈0.000 01） showed no significant difference in the rate of space closure. Conclusion Current clinical evidence indicates nickel titanium coil spring is superior to power chain in the rate of space closure, but its long-term effect still needs to be proved by more large-scale RCTs.

关 键 词：镍钛拉簧 弹力橡皮链 拔牙间隙 随机对照试验 META分析 系统评价 

分 类 号：R783.5[医药卫生—口腔医学]