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机构地区:[1]首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室,100730
出 处:《国际眼科纵览》2012年第4期285-288,共4页International Review of Ophthalmology
基 金:北京科技新星计划资助项目(2004836)
摘 要:甲状腺相关性眼病为常见眼眶病,其患病率在成人眼眶病中居首位。虽然目前其具体发病机制尚不完全清楚,但已证实甲状腺相关性眼病是一种自身免疫性疾病。本文通过对甲状腺相关性眼病的眼外肌、结缔组织、结膜等眼部组织的病理变化进行综述,为进一步揭示甲状腺相关性眼病的发病机制提供线索,对限制性斜视等一些临床现象提出更合理的解释,以期对临床治疗有一定指导意义。Thyroidassociated ophthalmopathy is the common orbital disease. Although the mecha nism is not fully understood, it has been confirmed that thyroidassociated ophthalmopathy is a kind of auto immune disease. The pathological changes of extraocular muscle connective tissue, and eye conjunctiva tissue in thyroidassociated ophthalmopathy were reviewed in this paper in order to provide some clues for fur ther revealling the pathogenesis of thyroidassociated ophthalmopathy, to present more reasonable explanation for some clinical phenomenon of the restrictive strabismus, and to expect some guiding for clinical treatment.
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