女性精神分裂症患者认知功能损害危险因素  

Risk Factors of Cognitive Impairment in Female Patients with Schizophrenia

作　　者：卢自祥[1] 孙旭锦[1] 卢智慧[1] 曾尚玲[1] 王丽芳[1] 

机构地区：[1]中国.云南省建水县红河州第二人民医院二病区,654300

出　　处：《中国健康心理学杂志》2012年第10期1473-1475,共3页China Journal of Health Psychology

摘　　要：目的探讨女性精神分裂症患者认知功能损害的危险因素,提供治疗认知功能损害的依据。方法采用自编调查表、阳性与阴性症状量表(PANSS)、简易智能精神状态量表(MMSE)对100例女性精神分裂症患者调查,认知功能损害危险因素采用Logistic回归分析。结果认知功能损害发生率为72%,阴性症状是认知功能损害的危险因素(B=0.151,Exp(B)=1.163),文化水平是认知功能损害的保护因素(B=-0.282,Exp(B)=0.754)。结论阴性症状越重认知功能损害危险度越高,文化水平越高认知功能损害危险度越低。Objective To explore risk factors of cognitive impairment in female patients with schizophrenia,and provide some basis for treatment of cognitive impairment.Methods A total of 100 female patients with schizophrenia were investigated by self-made questionnaire,the positive and negative symptom scale（PANSS）,mini-mental state examination（MMSE）,the risk factors for cognitive impairment was used logistic regression analysis.Results 72% of female patients with schizophrenia had cognitive impairment,negative symptoms was a risk factor for cognitive impairment（B=0.151,Exp（B）=1.163）,cultural level was a protective factor for cognitive impairment（B=-0.282,Exp（B）=0.754）.Conclusion The more severe the negative symptoms,the higher the risk of cognitive impairment.The higher the cultural level,the lower the risk of cognitive impairment.

关 键 词：精神分裂症 阴性症状 认知功能 回归分析 

分 类 号：R749.16[医药卫生—神经病学与精神病学]