鼻咽癌颈部转移淋巴结热放疗的临床疗效评价  

The evaluation of clinical efficacy about the radiohyperthermia for the nasopharyngeal carcinoma with neck metastasis lymph node

作　　者：牛东升 

机构地区：[1]河南省南阳市肿瘤医院放疗科,河南南阳473000

出　　处：《中国当代医药》2012年第26期36-37,共2页China Modern Medicine

摘　　要：目的探讨鼻咽癌颈部转移淋巴结热放疗的疗效及临床分析。方法将2010年6月~2012年6月本院诊治的48例鼻咽癌患者随机分为对照组（单纯放射性治疗）和观察组（放射性治疗后,给予局部热疗）,每组各24例,两组均给予氟尿嘧啶、顺铂联合化疗,化疗1~2个周期后,进行常规放疗,对两组患者的临床疗效及并发症进行观察和比较。结果与对照组（75.0%）相比,观察组的总有效率（100.0%）明显升高,P〈0.05;与对照组（33.3%）相比,观察组并发症的发生率（4.2%）明显降低,P〈0.05。结论对于颈部淋巴结转移的鼻咽癌患者,放疗后结合局部热疗疗效显著,并发症少,值得临床推广。Objective To investigate the evaluation of clinical efficacy about the radiohyperthermia for the patients of nasopharyngeal carcinoma with neck metastasis lymph node. Methods The 48 patients of nasopharyngeal carcinoma with neck metastasis lymph node from our hospital during the period from June 2010 to June 2012 were randomized into the control group （radiation therapy） and the observation group （local hyperthermia after the radioactive treatment）, 24 patients per group. The fluorouracil and cisplatin combined chemotherapy was 1-2 cycle, and then conventional radiotherapy was given to the two groups＇ patients. The clinical efficacy and complications were observed and compared. Results Compared with the control group （75.0%）, the total efficiency in the observation group was increased significantly （100.0%）, P 0.05; compared with the control group （33.3%）, the incidence of complications in the observation group was significantly lowered （4.2%）, P 0.05. Conclusion For the patients of nasopharyngeal carcinoma with neck metastasis lymph node, radiotherapy combined with local hyperthermia had the high clinical efficacy, less complications and worthy of clinical application.

关 键 词：鼻咽癌 淋巴结转移 热放疗 临床疗效 

分 类 号：R739.6[医药卫生—肿瘤]