异种脱细胞真皮基质膜在引导牙周组织再生中应用的临床效果评价  

Clinical Evaluation of Heterogeneous Acellular Dermal Matrix for Guided Tissue Regeneration in Periodontal Disease

作　　者：章立群[1] 邓碧霞[1] 谢安琪[1] 孙辉[1] 

机构地区：[1]广东医学院附属南山人民医院口腔科,广东深圳518052

出　　处：《口腔医学研究》2012年第11期1156-1159,共4页Journal of Oral Science Research

摘　　要：目的:评价异种脱细胞真皮基质膜在引导牙周组织再生中应用的临床效果。方法:30例牙周缺损区患牙随机分两组:实验组20例,异种脱细胞真皮基质膜和羟基磷灰石修复;对照组10例仅羟基磷灰石修复。统计学比较6个月时两组各项临床指标和牙槽骨水平改变。结果:实验组牙周袋深度、临床附着丧失的减少量和牙槽骨水平的增加量均较对照组高(P<0.05),牙龈退缩量低于对照组(P<0.05)。结论:异种脱细胞真皮基质膜应用于引导牙周组织再生有较好的临床效果,值得推广。Objective： To explore the clinical effectiveness of heterogeneous acellular dermal matrix（AMD） mem- brane for guided tissue regeneration in treatment of periodontal defects. Methods： 30 periodontal defects were ran- domly assigned into two treatments： 20 for testing group using a combination of AMD and coralline hydroxyapatite （HA） grafting and 10 for control group using HA grafting alone. After six months of surgery, the change of clinical index and radi6graphic alveolar bone level were compared statistically. Results： The reduction of pocket probing depth and clinical attachment loss and increasing level of alveolar bone of testing group were all higher than those in control group while the recession quantity was lower than that in control group（P〈0.05）. Conclusion： Heterogene- ous acellular dermal matrix membrane is effective for the treatment of periodontal defects.

关 键 词：异种脱细胞真皮基质 引导组织再生术 牙周缺损 

分 类 号：R781.4[医药卫生—口腔医学]