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作 者:高慧淳[1] 邹亮[1] 周建洪[1] 张芸[1] 欧阳莉[1]
机构地区:[1]南昌大学第三附属医院病理科,江西南昌330008
出 处:《武汉大学学报(医学版)》2012年第6期900-901,908,共3页Medical Journal of Wuhan University
摘 要:目的:探讨肠镜活检诊断结直肠癌的临床病理学特征。方法:回顾性分析98例经术后病理证实的结直肠癌患者肠镜活检的临床资料,并总结分析其临床病理特征。结果:98例患者性别无显著差异(P>0.05);≥55岁者(66例)显著多于<55岁者(32例)(P<0.01);病理类型以腺癌为主(83.7%),其中中分化腺癌占76.5%(75/98),低分化腺癌4.1%(4/98),黏液腺癌3.1%(3/98),未分化癌、印戒细胞癌及腺鳞癌、鳞癌等其它病理类型则较为少见;发病部位以直肠最为多见(70.5%),其次为左半结肠(26.5%)。结论:结直肠癌好发于年龄≥55岁老年人,且以直肠、左半结肠最为常见,而病理类型则以腺癌尤其是分化较高的腺癌最为常见,对于有不同程度大便习惯改变或黏液便、血便或大便性状改变等表现的老年患者进行肠镜检查,对该病的早期诊断具有重要意义。Objective: To discuss the clinicopathological characteristic diagnosis for colorectal cancer by colonoscopy.Methods: The clinical data and colonoscopy results of 98 patients with colorectal cancer confirmed by postoperative histopathologic examination were retrospective analyzed.Results: There was no significantly differences of gender between the 98 patients(P0.05),but the patients ≥55 years(n=66) were significantly more than those 55 years(P0.01),the most common pathological category was adenocarcinoma(83.7%),including moderately differentiated adenocarcinoma(76.5%),poorly differentiated adenocarcinoma(4.1%),and mucinous adenocarcinoma(3.1%).Other histological types were rare.Rectal cancer were the most common(70.5%),and the left colon cancer was the second(26.5%).Conclusion: Colorectal cancer commonly occurs at age≥55 years old;the rectum and the left colon are the most commonly involved sites;among the pathological types,adenocarcinoma,especially high differentiated adenocarcinoma,are common.It is important to perform colonoscopy early in the old patients with changes in stools.
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