60例肝性脑病患者预后的影响因素临床分析  

The prognostic risk factors of 60 cases of hepatic encephalopathy

作　　者：王丽梅[1] 吴颖[1] 

机构地区：[1]陕西省第二人民医院,陕西西安710005

出　　处：《中国美容医学》2012年第10X期172-173,共2页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨肝性脑病患者预后的危险因素,为临床治疗决策提供指导。方法:选取2009年1月～2012年2月在我院收治的60例肝性脑病患者,对所有患者行全面诊治与调查。结果:经过治疗后,肝性脑病患者的总体死亡率为25.0%。好转组与死亡组的Child-Pugh分级、基础疾病、MELD评分、血清胆红素、血清白蛋白、年龄指标对比差异有统计学意义(P<0.05)。多因素分析显示Child-Pugh分级、基础疾病、MELD评分、血清胆红素是影响肝性脑病患者预后的独立危险因素(P<0.05)。结论:肝性脑病的预后比较差,Child-Pugh分级、基础疾病、MELD评分与血清胆红素是主要的危险因素,要积极加强预防与对症处理。Objective To investigate the prognosis risk factors for hepatic encephalopathy patients to provide guidance for clinical decision making. Methods 60 cases of hepatic encephalopathy were admitted to our hospital from January 2009 to February 2012, all patients underwent a comprehensive diagnosis, treatment and investigation. Results After treatment, the overall mortality rate was 25.0%. The Child-Pugh score, underlying disease, MELD score, serum bilirubin, serum albumin, age had statistically significant between the improved group and the death group （P〈0.05）. Multivariate analysis showed that the Child-Pugh score, underlying disease, MELD score, serum bilirubin were the independent risk factor for the prognosis of hepatic encephalopathy （P〈0.05）. Conclusion The hepatic encephalopathy prognosis is relatively poor, the Child-Pugh score, underlying disease, MELD score and serum bilirubin are the main risk factors, we should actively strengthen the prevention and symptomatic treatment.

关 键 词：肝性脑病 预后 影响因素 Child—Pugh分级 

分 类 号：R747.9[医药卫生—神经病学与精神病学]